Retinal pigment epithelium changes in pediatric patients with glaucoma drainage devices
Purpose: Retinal changes secondary to hypotony are usually described as wrinkling or folding of the inner portion of the choroid, the retinal pigment epithelium (RPE), and the outer retinal layers in the macular area due to scleral wall collapse. We describe a new retinal finding in children with su...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-03-01
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| Series: | American Journal of Ophthalmology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993617300919 |
| _version_ | 1811283452383723520 |
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| author | Carla J. Osigian Sara Grace Maria P. Fernandez Camila V. Ventura Susan Azar Ta C. Chang Elizabeth Hodapp Sander R. Dubovy Audina Berrocal |
| author_facet | Carla J. Osigian Sara Grace Maria P. Fernandez Camila V. Ventura Susan Azar Ta C. Chang Elizabeth Hodapp Sander R. Dubovy Audina Berrocal |
| author_sort | Carla J. Osigian |
| collection | DOAJ |
| description | Purpose: Retinal changes secondary to hypotony are usually described as wrinkling or folding of the inner portion of the choroid, the retinal pigment epithelium (RPE), and the outer retinal layers in the macular area due to scleral wall collapse. We describe a new retinal finding in children with suspected hypotony after implantation of Baerveldt Glaucoma Implant (BGI).
Observations: Four patients in our series developed significant RPE defects after BGI implant. The RPE defects appeared as elongated white lines observed solely in the posterior pole, in no particular pattern, and seemed to be worse in infants with anterior segment dysgenesis and with collagen disorders.
Conclusion and importance: Children have thinner and more elastic scleral walls than adults. This characteristic may cause the inward scleral wall to collapse when the eye is hypotonic. The resulting redundancy of the retina leads to wrinkling and RPE defects characterized by hypopigmented lines predominantly in the macular area. Such findings, to our knowledge, have not been previously reported in pediatric patients. |
| first_indexed | 2024-04-13T02:11:38Z |
| format | Article |
| id | doaj.art-928ddf4190a44aad8066e548a6d24653 |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-04-13T02:11:38Z |
| publishDate | 2018-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-928ddf4190a44aad8066e548a6d246532022-12-22T03:07:17ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362018-03-019C232710.1016/j.ajoc.2017.12.001Retinal pigment epithelium changes in pediatric patients with glaucoma drainage devicesCarla J. Osigian0Sara Grace1Maria P. Fernandez2Camila V. Ventura3Susan Azar4Ta C. Chang5Elizabeth Hodapp6Sander R. Dubovy7Audina Berrocal8Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Department of Ophthalmology, 900 NW 17th St, Miami, FL, 33136, USAUniversity of North Carolina at Chapel Hill, Kittner Eye Center, 226 Nelson Hwy #200, Chapel Hill, NC, 27517, USABascom Palmer Eye Institute, University of Miami Miller School of Medicine, Department of Ophthalmology, 900 NW 17th St, Miami, FL, 33136, USABascom Palmer Eye Institute, University of Miami Miller School of Medicine, Department of Ophthalmology, 900 NW 17th St, Miami, FL, 33136, USATulane University School of Medicine, Department of Ophthalmology, 1430 Tulane Avenue, Suite 5013, New Orleans, LA, 70112, USABascom Palmer Eye Institute, University of Miami Miller School of Medicine, Department of Ophthalmology, 900 NW 17th St, Miami, FL, 33136, USABascom Palmer Eye Institute, University of Miami Miller School of Medicine, Department of Ophthalmology, 900 NW 17th St, Miami, FL, 33136, USABascom Palmer Eye Institute, University of Miami Miller School of Medicine, Department of Ophthalmology, 900 NW 17th St, Miami, FL, 33136, USABascom Palmer Eye Institute, University of Miami Miller School of Medicine, Department of Ophthalmology, 900 NW 17th St, Miami, FL, 33136, USAPurpose: Retinal changes secondary to hypotony are usually described as wrinkling or folding of the inner portion of the choroid, the retinal pigment epithelium (RPE), and the outer retinal layers in the macular area due to scleral wall collapse. We describe a new retinal finding in children with suspected hypotony after implantation of Baerveldt Glaucoma Implant (BGI). Observations: Four patients in our series developed significant RPE defects after BGI implant. The RPE defects appeared as elongated white lines observed solely in the posterior pole, in no particular pattern, and seemed to be worse in infants with anterior segment dysgenesis and with collagen disorders. Conclusion and importance: Children have thinner and more elastic scleral walls than adults. This characteristic may cause the inward scleral wall to collapse when the eye is hypotonic. The resulting redundancy of the retina leads to wrinkling and RPE defects characterized by hypopigmented lines predominantly in the macular area. Such findings, to our knowledge, have not been previously reported in pediatric patients.http://www.sciencedirect.com/science/article/pii/S2451993617300919HypotonyRetinal pigment epitheliumBaerveldt glaucoma implantHypopigmented linesScleral elasticity |
| spellingShingle | Carla J. Osigian Sara Grace Maria P. Fernandez Camila V. Ventura Susan Azar Ta C. Chang Elizabeth Hodapp Sander R. Dubovy Audina Berrocal Retinal pigment epithelium changes in pediatric patients with glaucoma drainage devices American Journal of Ophthalmology Case Reports Hypotony Retinal pigment epithelium Baerveldt glaucoma implant Hypopigmented lines Scleral elasticity |
| title | Retinal pigment epithelium changes in pediatric patients with glaucoma drainage devices |
| title_full | Retinal pigment epithelium changes in pediatric patients with glaucoma drainage devices |
| title_fullStr | Retinal pigment epithelium changes in pediatric patients with glaucoma drainage devices |
| title_full_unstemmed | Retinal pigment epithelium changes in pediatric patients with glaucoma drainage devices |
| title_short | Retinal pigment epithelium changes in pediatric patients with glaucoma drainage devices |
| title_sort | retinal pigment epithelium changes in pediatric patients with glaucoma drainage devices |
| topic | Hypotony Retinal pigment epithelium Baerveldt glaucoma implant Hypopigmented lines Scleral elasticity |
| url | http://www.sciencedirect.com/science/article/pii/S2451993617300919 |
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