Serum Zinc Level in Neonates with Indirect Hyperbilirubinemia
Background: The most common cause of hospital admission in the first month of life is the neonatal jaundice. Some factors [e.g., prenatal, neonatal factors, maternal factors, and environmental factors (such as zinc) influence the frequency of neonatal jaundice. In terms of neonates, it is proposed t...
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| Format: | Article |
| Language: | English |
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Al-Azhar University, Faculty of Medicine (Damietta)
2020-01-01
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| Series: | International Journal of Medical Arts |
| Subjects: | |
| Online Access: | https://ijma.journals.ekb.eg/article_65788_cc5f68a0d8d7e663ba7ad2debd8fb752.pdf |
| _version_ | 1818858550588342272 |
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| author | Saeda Ali Mohamed Abdel-aal Mohamed Elsamanoudy Sabah Ibrahim |
| author_facet | Saeda Ali Mohamed Abdel-aal Mohamed Elsamanoudy Sabah Ibrahim |
| author_sort | Saeda Ali |
| collection | DOAJ |
| description | Background: The most common cause of hospital admission in the first month of life is the neonatal jaundice. Some factors [e.g., prenatal, neonatal factors, maternal factors, and environmental factors (such as zinc) influence the frequency of neonatal jaundice. In terms of neonates, it is proposed that there is a correlation between serum zinc quality and hyperbilirubinemia. Aim of the work: To evaluate the level of serum zinc in term neonates with indirect hyperbilirubinemia. Patients and Methods: A case control study carried out at the neonatal intensive care unit (NICU) and pediatric outpatient clinic of New Damietta, Al-Azhar University Hospital, from June 2018 to February 2019. It included 75 neonates with neonatal jaundice as cases group and 75 healthy neonates of matched age and sex as a control group. All were assessed clinically and serum zinc levels were determined and documented. Results: Level of serum zinc in neonates with non-hemolytic hyperbilirubinemia (103.3±36.56 ug/dl) was significantly lower than healthy neonates without jaundice (128.62 ± 40.83 ug/dl) and zinc deficiency in jaundiced neonates (25.3%) was statistically significant more than healthy neonates) 6.7%). There was no significant relation between the level of serum zinc and other factors like the maternal age, parity, pattern of feeding, gender and weight, but there was significant correlation with maternal zinc intake during pregnancy. Conclusion: We concluded that serum zinc level in term neonates with neonatal jaundice was statistically significant decreased than healthy term neonates. |
| first_indexed | 2024-12-19T08:58:04Z |
| format | Article |
| id | doaj.art-928f81beaae7458c89bae9e97b5d2807 |
| institution | Directory Open Access Journal |
| issn | 2636-4174 2682-3780 |
| language | English |
| last_indexed | 2024-12-19T08:58:04Z |
| publishDate | 2020-01-01 |
| publisher | Al-Azhar University, Faculty of Medicine (Damietta) |
| record_format | Article |
| series | International Journal of Medical Arts |
| spelling | doaj.art-928f81beaae7458c89bae9e97b5d28072022-12-21T20:28:34ZengAl-Azhar University, Faculty of Medicine (Damietta)International Journal of Medical Arts2636-41742682-37802020-01-012121722210.21608/ijma.2019.18377.103865788Serum Zinc Level in Neonates with Indirect HyperbilirubinemiaSaeda Ali0Mohamed Abdel-aal1Mohamed Elsamanoudy2Sabah Ibrahim3Department of Pediatrics, Kafr-Elsheikh General Hospital, Ministry of Health, EgyptDepartment of Pediatrics, Damietta Faculty of Medicine, Al-Azhar University, Egypt.Department of Pediatrics, Damietta Faculty of Medicine, Al-Azhar University, EgyptDepartment of Clinical Pathology, Damietta Faculty of Medicine, Al-Azhar university, Egypt.Background: The most common cause of hospital admission in the first month of life is the neonatal jaundice. Some factors [e.g., prenatal, neonatal factors, maternal factors, and environmental factors (such as zinc) influence the frequency of neonatal jaundice. In terms of neonates, it is proposed that there is a correlation between serum zinc quality and hyperbilirubinemia. Aim of the work: To evaluate the level of serum zinc in term neonates with indirect hyperbilirubinemia. Patients and Methods: A case control study carried out at the neonatal intensive care unit (NICU) and pediatric outpatient clinic of New Damietta, Al-Azhar University Hospital, from June 2018 to February 2019. It included 75 neonates with neonatal jaundice as cases group and 75 healthy neonates of matched age and sex as a control group. All were assessed clinically and serum zinc levels were determined and documented. Results: Level of serum zinc in neonates with non-hemolytic hyperbilirubinemia (103.3±36.56 ug/dl) was significantly lower than healthy neonates without jaundice (128.62 ± 40.83 ug/dl) and zinc deficiency in jaundiced neonates (25.3%) was statistically significant more than healthy neonates) 6.7%). There was no significant relation between the level of serum zinc and other factors like the maternal age, parity, pattern of feeding, gender and weight, but there was significant correlation with maternal zinc intake during pregnancy. Conclusion: We concluded that serum zinc level in term neonates with neonatal jaundice was statistically significant decreased than healthy term neonates.https://ijma.journals.ekb.eg/article_65788_cc5f68a0d8d7e663ba7ad2debd8fb752.pdfzincindirecthemolytichyperbilirubinemianeonates |
| spellingShingle | Saeda Ali Mohamed Abdel-aal Mohamed Elsamanoudy Sabah Ibrahim Serum Zinc Level in Neonates with Indirect Hyperbilirubinemia International Journal of Medical Arts zinc indirect hemolytic hyperbilirubinemia neonates |
| title | Serum Zinc Level in Neonates with Indirect Hyperbilirubinemia |
| title_full | Serum Zinc Level in Neonates with Indirect Hyperbilirubinemia |
| title_fullStr | Serum Zinc Level in Neonates with Indirect Hyperbilirubinemia |
| title_full_unstemmed | Serum Zinc Level in Neonates with Indirect Hyperbilirubinemia |
| title_short | Serum Zinc Level in Neonates with Indirect Hyperbilirubinemia |
| title_sort | serum zinc level in neonates with indirect hyperbilirubinemia |
| topic | zinc indirect hemolytic hyperbilirubinemia neonates |
| url | https://ijma.journals.ekb.eg/article_65788_cc5f68a0d8d7e663ba7ad2debd8fb752.pdf |
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