SSRI-associated apathy in Alzheimer's disease: a case series
Apathy is one of the most common manifestations of neurodegenerative pathology, including Alzheimer's disease (AD). Despite such a significant role of apathy in the course of the disease, there are no unambiguous recommendations for the treatment and prevention of this symptom complex. Some cla...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IMA-PRESS LLC
2022-08-01
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| Series: | Неврология, нейропсихиатрия, психосоматика |
| Subjects: | |
| Online Access: | https://nnp.ima-press.net/nnp/article/view/1861 |
| _version_ | 1827062729461989376 |
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| author | D. S. Petelin A. N. Gamirova O. N. Voskresenskaya B. A. Volel |
| author_facet | D. S. Petelin A. N. Gamirova O. N. Voskresenskaya B. A. Volel |
| author_sort | D. S. Petelin |
| collection | DOAJ |
| description | Apathy is one of the most common manifestations of neurodegenerative pathology, including Alzheimer's disease (AD). Despite such a significant role of apathy in the course of the disease, there are no unambiguous recommendations for the treatment and prevention of this symptom complex. Some classes of psychotropic drugs commonly prescribed for AD, such as antidepressants of the SSRI class, may themselves cause apathy. The authors present a series of clinical observations describing four cases of deterioration in the condition of patients with AD during SSRI therapy. The features of the clinical course of the disease are discussed, new strategies for drug therapy are proposed. |
| first_indexed | 2024-04-10T02:01:05Z |
| format | Article |
| id | doaj.art-9291c3de18994a98864b87c11e01662f |
| institution | Directory Open Access Journal |
| issn | 2074-2711 2310-1342 |
| language | Russian |
| last_indexed | 2025-02-18T20:01:31Z |
| publishDate | 2022-08-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Неврология, нейропсихиатрия, психосоматика |
| spelling | doaj.art-9291c3de18994a98864b87c11e01662f2024-10-17T16:15:30ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422022-08-01144515310.14412/2074-2711-2022-4-51-531289SSRI-associated apathy in Alzheimer's disease: a case seriesD. S. Petelin0A. N. Gamirova1O. N. Voskresenskaya2B. A. Volel3I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaI.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaApathy is one of the most common manifestations of neurodegenerative pathology, including Alzheimer's disease (AD). Despite such a significant role of apathy in the course of the disease, there are no unambiguous recommendations for the treatment and prevention of this symptom complex. Some classes of psychotropic drugs commonly prescribed for AD, such as antidepressants of the SSRI class, may themselves cause apathy. The authors present a series of clinical observations describing four cases of deterioration in the condition of patients with AD during SSRI therapy. The features of the clinical course of the disease are discussed, new strategies for drug therapy are proposed.https://nnp.ima-press.net/nnp/article/view/1861apathyneurodegenerative diseasesalzheimer's diseaseantidepressantsssris |
| spellingShingle | D. S. Petelin A. N. Gamirova O. N. Voskresenskaya B. A. Volel SSRI-associated apathy in Alzheimer's disease: a case series Неврология, нейропсихиатрия, психосоматика apathy neurodegenerative diseases alzheimer's disease antidepressants ssris |
| title | SSRI-associated apathy in Alzheimer's disease: a case series |
| title_full | SSRI-associated apathy in Alzheimer's disease: a case series |
| title_fullStr | SSRI-associated apathy in Alzheimer's disease: a case series |
| title_full_unstemmed | SSRI-associated apathy in Alzheimer's disease: a case series |
| title_short | SSRI-associated apathy in Alzheimer's disease: a case series |
| title_sort | ssri associated apathy in alzheimer s disease a case series |
| topic | apathy neurodegenerative diseases alzheimer's disease antidepressants ssris |
| url | https://nnp.ima-press.net/nnp/article/view/1861 |
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