Refractory Hypoglycaemia in Hepatocellular Carcinoma Treated with TACE Leading to Tumour Lysis Syndrome- A Double Trouble

Hepatocellular Carcinoma (HCC) is the most common type of primary liver cancer. Hypoglycaemia is a well-established paraneoplastic manifestation of HCC. Cytoreduction by surgery or Transarterial Chemoembolisation (TACE) has been effective treatment options in such cases when conservative treatment f...

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Main Authors: Saurabh kumar, Ishita B Sen, Vivek Vij, Ashish Singhal, Ajitabh Srivastava
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2022-01-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://www.jcdr.net/articles/PDF/15923/52274_CE(Ra1)_F(SS)_PF1(SC_SS)_PFA(SC_KM)_PN(KM).pdf
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author Saurabh kumar
Ishita B Sen
Vivek Vij
Ashish Singhal
Ajitabh Srivastava
author_facet Saurabh kumar
Ishita B Sen
Vivek Vij
Ashish Singhal
Ajitabh Srivastava
author_sort Saurabh kumar
collection DOAJ
description Hepatocellular Carcinoma (HCC) is the most common type of primary liver cancer. Hypoglycaemia is a well-established paraneoplastic manifestation of HCC. Cytoreduction by surgery or Transarterial Chemoembolisation (TACE) has been effective treatment options in such cases when conservative treatment fails. Tumour Lysis Syndrome (TLS) is an oncological emergency following treatment of malignancies with high cell turnover and can be seen in liver-directed therapy in the form of both ablative therapies and transarterial therapies for HCC. Authors present a rare case of 65-year-old male, with HCC presented with symptoms of refractory hypoglycaemia which was managed by TACE procedure with further patient developing TLS which was medically managed.
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spelling doaj.art-92921416518d4c87b3af5bf5322af6c12023-01-31T04:21:21ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2022-01-01161TD01TD0210.7860/JCDR/2022/52274.15923Refractory Hypoglycaemia in Hepatocellular Carcinoma Treated with TACE Leading to Tumour Lysis Syndrome- A Double TroubleSaurabh kumar0Ishita B Sen1Vivek Vij2Ashish Singhal3Ajitabh Srivastava4Consultant Interventional Radiologist, Department of Interventional Radiology, Fortis Memorial Research Institute, Gurugram, Haryana, India.Director, Department of Nuclear Medicine, Fortis Memorial Research Institute, Gurugram, Haryana, India.Director, Department of Liver Transplant and Hepatobiliary Surgery, Fortis Memorial Research Institute, Gurugram, Haryana, India.Senior Consultant, Department of Liver Transplant and Hepatobiliary Surgery, Fortis Memorial Research Institute, Gurugram, Haryana, India.Senior Consultant, Department of Liver Transplant and Hepatobiliary Surgery, Fortis Memorial Research Institute, Gurugram, Haryana, India.Hepatocellular Carcinoma (HCC) is the most common type of primary liver cancer. Hypoglycaemia is a well-established paraneoplastic manifestation of HCC. Cytoreduction by surgery or Transarterial Chemoembolisation (TACE) has been effective treatment options in such cases when conservative treatment fails. Tumour Lysis Syndrome (TLS) is an oncological emergency following treatment of malignancies with high cell turnover and can be seen in liver-directed therapy in the form of both ablative therapies and transarterial therapies for HCC. Authors present a rare case of 65-year-old male, with HCC presented with symptoms of refractory hypoglycaemia which was managed by TACE procedure with further patient developing TLS which was medically managed.https://www.jcdr.net/articles/PDF/15923/52274_CE(Ra1)_F(SS)_PF1(SC_SS)_PFA(SC_KM)_PN(KM).pdfcytoreductionhepatomegalytransarterial chemoembolisation
spellingShingle Saurabh kumar
Ishita B Sen
Vivek Vij
Ashish Singhal
Ajitabh Srivastava
Refractory Hypoglycaemia in Hepatocellular Carcinoma Treated with TACE Leading to Tumour Lysis Syndrome- A Double Trouble
Journal of Clinical and Diagnostic Research
cytoreduction
hepatomegaly
transarterial chemoembolisation
title Refractory Hypoglycaemia in Hepatocellular Carcinoma Treated with TACE Leading to Tumour Lysis Syndrome- A Double Trouble
title_full Refractory Hypoglycaemia in Hepatocellular Carcinoma Treated with TACE Leading to Tumour Lysis Syndrome- A Double Trouble
title_fullStr Refractory Hypoglycaemia in Hepatocellular Carcinoma Treated with TACE Leading to Tumour Lysis Syndrome- A Double Trouble
title_full_unstemmed Refractory Hypoglycaemia in Hepatocellular Carcinoma Treated with TACE Leading to Tumour Lysis Syndrome- A Double Trouble
title_short Refractory Hypoglycaemia in Hepatocellular Carcinoma Treated with TACE Leading to Tumour Lysis Syndrome- A Double Trouble
title_sort refractory hypoglycaemia in hepatocellular carcinoma treated with tace leading to tumour lysis syndrome a double trouble
topic cytoreduction
hepatomegaly
transarterial chemoembolisation
url https://www.jcdr.net/articles/PDF/15923/52274_CE(Ra1)_F(SS)_PF1(SC_SS)_PFA(SC_KM)_PN(KM).pdf
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AT vivekvij refractoryhypoglycaemiainhepatocellularcarcinomatreatedwithtaceleadingtotumourlysissyndromeadoubletrouble
AT ashishsinghal refractoryhypoglycaemiainhepatocellularcarcinomatreatedwithtaceleadingtotumourlysissyndromeadoubletrouble
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