Fat, Sugar or Gut Microbiota in Reducing Cardiometabolic Risk: Does Diet Type Really Matter?

The incidence of cardiometabolic diseases, such as obesity, diabetes, and cardiovascular diseases, is constantly rising. Successful lifestyle changes may limit their incidence, which is why researchers focus on the role of nutrition in this context. The outcomes of studies carried out in past decade...

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Main Authors: Katarzyna Nabrdalik, Katarzyna Krzyżak, Weronika Hajzler, Karolina Drożdż, Hanna Kwiendacz, Janusz Gumprecht, Gregory Y. H. Lip
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/13/2/639
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author Katarzyna Nabrdalik
Katarzyna Krzyżak
Weronika Hajzler
Karolina Drożdż
Hanna Kwiendacz
Janusz Gumprecht
Gregory Y. H. Lip
author_facet Katarzyna Nabrdalik
Katarzyna Krzyżak
Weronika Hajzler
Karolina Drożdż
Hanna Kwiendacz
Janusz Gumprecht
Gregory Y. H. Lip
author_sort Katarzyna Nabrdalik
collection DOAJ
description The incidence of cardiometabolic diseases, such as obesity, diabetes, and cardiovascular diseases, is constantly rising. Successful lifestyle changes may limit their incidence, which is why researchers focus on the role of nutrition in this context. The outcomes of studies carried out in past decades have influenced dietary guidelines, which primarily recommend reducing saturated fat as a therapeutic approach for cardiovascular disease prevention, while limiting the role of sugar due to its harmful effects. On the other hand, a low-carbohydrate diet (LCD) as a method of treatment remains controversial. A number of studies on the effect of LCDs on patients with type 2 diabetes mellitus proved that it is a safe and effective method of dietary management. As for the risk of cardiovascular diseases, the source of carbohydrates and fats corresponds with the mortality rate and protective effect of plant-derived components. Additionally, some recent studies have focused on the gut microbiota in relation to cardiometabolic diseases and diet as one of the leading factors affecting microbiota composition. Unfortunately, there is still no precise answer to the question of which a single nutrient plays the most important role in reducing cardiometabolic risk, and this review article presents the current state of the knowledge in this field.
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spelling doaj.art-929724c0198b47f18359148227acbc1f2023-12-11T17:16:10ZengMDPI AGNutrients2072-66432021-02-0113263910.3390/nu13020639Fat, Sugar or Gut Microbiota in Reducing Cardiometabolic Risk: Does Diet Type Really Matter?Katarzyna Nabrdalik0Katarzyna Krzyżak1Weronika Hajzler2Karolina Drożdż3Hanna Kwiendacz4Janusz Gumprecht5Gregory Y. H. Lip6Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool L14 3PE, UKStudents’ Scientific Association by the Department of Internal Medicine, Diabetology and Nephrology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, PolandStudents’ Scientific Association by the Department of Internal Medicine, Diabetology and Nephrology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, PolandDepartment of Internal Medicine, Diabetology and Nephrology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, PolandDepartment of Internal Medicine, Diabetology and Nephrology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, PolandDepartment of Internal Medicine, Diabetology and Nephrology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, PolandLiverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool L14 3PE, UKThe incidence of cardiometabolic diseases, such as obesity, diabetes, and cardiovascular diseases, is constantly rising. Successful lifestyle changes may limit their incidence, which is why researchers focus on the role of nutrition in this context. The outcomes of studies carried out in past decades have influenced dietary guidelines, which primarily recommend reducing saturated fat as a therapeutic approach for cardiovascular disease prevention, while limiting the role of sugar due to its harmful effects. On the other hand, a low-carbohydrate diet (LCD) as a method of treatment remains controversial. A number of studies on the effect of LCDs on patients with type 2 diabetes mellitus proved that it is a safe and effective method of dietary management. As for the risk of cardiovascular diseases, the source of carbohydrates and fats corresponds with the mortality rate and protective effect of plant-derived components. Additionally, some recent studies have focused on the gut microbiota in relation to cardiometabolic diseases and diet as one of the leading factors affecting microbiota composition. Unfortunately, there is still no precise answer to the question of which a single nutrient plays the most important role in reducing cardiometabolic risk, and this review article presents the current state of the knowledge in this field.https://www.mdpi.com/2072-6643/13/2/639carbohydratesdiabetes mellitusdietfatmicrobiota
spellingShingle Katarzyna Nabrdalik
Katarzyna Krzyżak
Weronika Hajzler
Karolina Drożdż
Hanna Kwiendacz
Janusz Gumprecht
Gregory Y. H. Lip
Fat, Sugar or Gut Microbiota in Reducing Cardiometabolic Risk: Does Diet Type Really Matter?
Nutrients
carbohydrates
diabetes mellitus
diet
fat
microbiota
title Fat, Sugar or Gut Microbiota in Reducing Cardiometabolic Risk: Does Diet Type Really Matter?
title_full Fat, Sugar or Gut Microbiota in Reducing Cardiometabolic Risk: Does Diet Type Really Matter?
title_fullStr Fat, Sugar or Gut Microbiota in Reducing Cardiometabolic Risk: Does Diet Type Really Matter?
title_full_unstemmed Fat, Sugar or Gut Microbiota in Reducing Cardiometabolic Risk: Does Diet Type Really Matter?
title_short Fat, Sugar or Gut Microbiota in Reducing Cardiometabolic Risk: Does Diet Type Really Matter?
title_sort fat sugar or gut microbiota in reducing cardiometabolic risk does diet type really matter
topic carbohydrates
diabetes mellitus
diet
fat
microbiota
url https://www.mdpi.com/2072-6643/13/2/639
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