Mathematical Model to Predict Skin Concentration after Topical Application of Drugs

Mathematical Model to Predict Skin Concentration after Topical Application of Drugs

Skin permeation experiments have been broadly done since 1970s to 1980s as an evaluation method for transdermal drug delivery systems. In topically applied drug and cosmetic formulations, skin concentration of chemical compounds is more important than their skin permeations, because primary target s...

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Bibliographic Details
Main Authors: Hiroaki Todo, Takeshi Oshizaka, Wesam R. Kadhum, Kenji Sugibayashi
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:Pharmaceutics
Subjects:
skin permeation
skin concentration
silicone membrane
permeation profile
Online Access:http://www.mdpi.com/1999-4923/5/4/634

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