Should We Still Use Therapeutic Plasma Exchange for Rapidly Progressive Glomerulonephritis in ANCA Associated Vasculitis?
For over thirty-five years, available data suggested that therapeutic plasma exchange (TPE) was a useful treatment for patients with Rapidly Progressive Glomerulonephritis (RPGN) associated with ANCA Associated Vasculitis (AAV) and elevated creatinine levels. The publication of the PEXIVAS study has...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Kidney and Dialysis |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-8236/2/3/35 |
| _version_ | 1797464846031126528 |
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| author | Andre A. Kaplan Wladimir M. Szpirt |
| author_facet | Andre A. Kaplan Wladimir M. Szpirt |
| author_sort | Andre A. Kaplan |
| collection | DOAJ |
| description | For over thirty-five years, available data suggested that therapeutic plasma exchange (TPE) was a useful treatment for patients with Rapidly Progressive Glomerulonephritis (RPGN) associated with ANCA Associated Vasculitis (AAV) and elevated creatinine levels. The publication of the PEXIVAS study has challenged this conclusion. This perspective will outline the history of this issue and present our assessment of the current status. |
| first_indexed | 2024-03-09T18:13:57Z |
| format | Article |
| id | doaj.art-929847f754894f25ac886dcc827d6509 |
| institution | Directory Open Access Journal |
| issn | 2673-8236 |
| language | English |
| last_indexed | 2024-03-09T18:13:57Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Kidney and Dialysis |
| spelling | doaj.art-929847f754894f25ac886dcc827d65092023-11-24T08:54:56ZengMDPI AGKidney and Dialysis2673-82362022-07-012339940610.3390/kidneydial2030035Should We Still Use Therapeutic Plasma Exchange for Rapidly Progressive Glomerulonephritis in ANCA Associated Vasculitis?Andre A. Kaplan0Wladimir M. Szpirt1Division of Nephrology, University of Connecticut Health Center, Farmington, CT 06062, USADepartment of Nephrology, Rigshospitalet, University of Copenhagen, 2100 Copenhagen, DenmarkFor over thirty-five years, available data suggested that therapeutic plasma exchange (TPE) was a useful treatment for patients with Rapidly Progressive Glomerulonephritis (RPGN) associated with ANCA Associated Vasculitis (AAV) and elevated creatinine levels. The publication of the PEXIVAS study has challenged this conclusion. This perspective will outline the history of this issue and present our assessment of the current status.https://www.mdpi.com/2673-8236/2/3/35therapeutic plasma exchangePLEXRPGNANCAPEXIVAS |
| spellingShingle | Andre A. Kaplan Wladimir M. Szpirt Should We Still Use Therapeutic Plasma Exchange for Rapidly Progressive Glomerulonephritis in ANCA Associated Vasculitis? Kidney and Dialysis therapeutic plasma exchange PLEX RPGN ANCA PEXIVAS |
| title | Should We Still Use Therapeutic Plasma Exchange for Rapidly Progressive Glomerulonephritis in ANCA Associated Vasculitis? |
| title_full | Should We Still Use Therapeutic Plasma Exchange for Rapidly Progressive Glomerulonephritis in ANCA Associated Vasculitis? |
| title_fullStr | Should We Still Use Therapeutic Plasma Exchange for Rapidly Progressive Glomerulonephritis in ANCA Associated Vasculitis? |
| title_full_unstemmed | Should We Still Use Therapeutic Plasma Exchange for Rapidly Progressive Glomerulonephritis in ANCA Associated Vasculitis? |
| title_short | Should We Still Use Therapeutic Plasma Exchange for Rapidly Progressive Glomerulonephritis in ANCA Associated Vasculitis? |
| title_sort | should we still use therapeutic plasma exchange for rapidly progressive glomerulonephritis in anca associated vasculitis |
| topic | therapeutic plasma exchange PLEX RPGN ANCA PEXIVAS |
| url | https://www.mdpi.com/2673-8236/2/3/35 |
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