The protective role of FTY720 in promoting survival of allograft fat in mice

The protective role of FTY720 in promoting survival of allograft fat in mice

Abstract Fat transplantation is widely used for soft‐tissue filling and wound repair. Owing to the biological changes in adipocytes in some metabolic diseases, allograft fat can provide a better source of donor fat than autologous fat. Fingolimod (FTY720) possesses a powerful immunomodulatory functi...

Full description

Bibliographic Details
Main Authors:	Yi Yi, Wei‐Jie Hu, Chong‐Ru Zhao, Ming‐Chen Xiong, Qi Zhang, Yi‐Ping Wu, Hong Zeng, Ning Zeng
Format:	Article
Language:	English
Published:	Wiley 2022-09-01
Series:	Kaohsiung Journal of Medical Sciences
Subjects:	allograft fat survival FTY720 graft inflammatory cells
Online Access:	https://doi.org/10.1002/kjm2.12570

Similar Items

The imbalance between Treg and Th17 cells caused by FTY720 treatment in skin allograft rejection
by: Alessandra Gonçalves Commodaro, et al.
Published: (2012-07-01)

Pharmacokinetic/pharmacodynamic relationships of FTY720 in kidney transplant recipients
by: S.I. Park, et al.
Published: (2005-05-01)

FTY720 controls disease severity and attenuates sciatic nerve damage in chronic experimental autoimmune neuritis
by: Laurent Kremer, et al.
Published: (2019-03-01)

Metformin and FTY720 Synergistically Induce Apoptosis in Multiple Myeloma Cells
by: Yi Zhao, et al.
Published: (2018-07-01)

Cardioprotective Effects of Sphingosine-1-Phosphate Receptor Immunomodulator FTY720 in a Clinically Relevant Model of Cardioplegic Arrest and Cardiopulmonary Bypass
by: Naseer Ahmed, et al.
Published: (2019-07-01)

Differential effects of FTY720 on the B cell compartment in a mouse model of multiple sclerosis
by: Kathrin Bail, et al.
Published: (2017-07-01)

Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging
by: Jie Zhang, et al.
Published: (2020-01-01)

The functional antagonist of sphingosine-1-phosphate, FTY720, impairs gut barrier function
by: Sohini Sikdar, et al.
Published: (2024-08-01)

Effect of FTY720 on transfusion-related acute lung injury: a preliminary investigation
by: Yaling ZHOU, et al.
Published: (2023-05-01)

The Effects of the S1P Receptor Agonist Fingolimod (FTY720) on Central and Peripheral Myelin in Twitcher Mice
by: Sibylle Béchet, et al.
Published: (2024-03-01)

FTY720 in immuno-regenerative and wound healing technologies for muscle, epithelial and bone regeneration
by: Monica Behara, et al.
Published: (2023-05-01)

A genome-wide screen for FTY720-sensitive mutants reveals genes required for ROS homeostasis
by: Kanako Hagihara, et al.
Published: (2017-11-01)

Anti-tumor drug FTY720 regulates p53-dependent transcription
by: YAO Han, XU Wen-bin, WANG Dong-lai
Published: (2021-03-01)

Peripheral T Cell Depletion by FTY720 Exacerbates Hypoxic-Ischemic Brain Injury in Neonatal Mice
by: Josephine Herz, et al.
Published: (2018-08-01)

FTY720 ameliorates GvHD by blocking T lymphocyte migration to target organs and by skin fibrosis inhibition
by: Jaeyoon Ryu, et al.
Published: (2020-06-01)

Behavioral Analyses in Dark Agouti Rats Following Repeated Systemic Treatment With Fingolimod (FTY720)
by: Marie Jakobs, et al.
Published: (2024-11-01)

Synthesis of Novel FTY720 Analogs with Anticancer Activity through PP2A Activation
by: Jitendra Shrestha, et al.
Published: (2018-10-01)

FTY720 Regulates Mitochondria Biogenesis in Dendritic Cells to Prevent Kidney Ischemic Reperfusion Injury
by: Thomas V. Rousselle, et al.
Published: (2020-06-01)

FTY720 Inhibits the Development of Collagen-Induced Arthritis in Mice by Suppressing the Recruitment of CD4+ T Lymphocytes
by: Zhu C, et al.
Published: (2021-05-01)

Presynaptic Release-Regulating Sphingosine 1-Phosphate 1/3 Receptors in Cortical Glutamatergic Terminals: Adaptations in EAE Mice and Impact of Therapeutic FTY720
by: Alessandra Roggeri, et al.
Published: (2023-09-01)

FTY720 Reduces the Biomass of Biofilms in <i>Pseudomonas aeruginosa</i> in a Dose-Dependent Manner
by: Abdurahman A. Niazy, et al.
Published: (2024-07-01)

Effects of FTY720 on brain neurogenic niches in vitro and after kainic acid-induced injury
by: Raffaela Cipriani, et al.
Published: (2017-07-01)

Therapeutic approach to mite-induced intractable dermatitis using novel immunomodulator FTY720 ointment (fingolimod) in NC/Nga mice
by: Takumi Tsuji, et al.
Published: (2016-04-01)

FTY720 Exerts Anti-Glioma Effects by Regulating the Glioma Microenvironment Through Increased CXCR4 Internalization by Glioma-Associated Microglia
by: Xu-Dong Guo, et al.
Published: (2020-03-01)

Inhibition of basal-like breast cancer growth by FTY720 in combination with epidermal growth factor receptor kinase blockade
by: Janet L. Martin, et al.
Published: (2017-08-01)

The emerging role of FTY720 as a sphingosine 1‐phosphate analog for the treatment of ischemic stroke: The cellular and molecular mechanisms
by: Maryam Naseh, et al.
Published: (2021-06-01)

Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis
by: Sahar A. Saddoughi, et al.
Published: (2012-11-01)

The Immunosuppressant FTY720 (Fingolimod) enhances Glycosaminoglycan depletion in articular cartilage
by: Stradner Martin H, et al.
Published: (2011-12-01)

Sex-dependent efficacy of sphingosine-1-phosphate receptor agonist FTY720 in mitigating Huntington’s disease
by: Jingyun Wu, et al.
Published: (2025-01-01)

Injectable Hydrogel Loaded with CDs and FTY720 Combined with Neural Stem Cells for the Treatment of Spinal Cord Injury
by: Qi Z, et al.
Published: (2024-05-01)

FTY720 induces apoptosis in B16F10-NEX2 murine melanoma cells, limits metastatic development in vivo, and modulates the immune system
by: Felipe V. Pereira, et al.
Published: (2013-07-01)

Effect of immunomodulator, fingolimod, on ischemia reperfusion testicular injury in rats: Targeting the role of sphingolipid rheostat (fingolimod on I/R induced testicular injury)
by: Marwa N. Emam, et al.
Published: (2017-06-01)

FTY720-derivatives do not induce FTY720-like lymphopenia
by: Ismael Segura-Ulate, et al.
Published: (2017-03-01)

Platelet Membrane Nanocarriers Cascade Targeting Delivery System to Improve Myocardial Remodeling Post Myocardial Ischemia–Reperfusion Injury
by: Xuan Xu, et al.
Published: (2024-04-01)

Sphingosine kinase 1 overexpression contributes to sunitinib resistance in clear cell renal cell carcinoma
by: Yunze Xu, et al.
Published: (2018-12-01)

Cele rozwoju austriackiego systemu badań, technologii i innowacji przez pryzmat FTI-Strategie 2030
by: Krzysztof Szewior
Published: (2024-12-01)

Actions of FTY720 (Fingolimod), a Sphingosine-1-Phosphate Receptor Modulator, on Delayed-Rectifier K<sup>+</sup> Current and Intermediate-Conductance Ca<sup>2+</sup>-Activated K<sup>+</sup> Channel in Jurkat T-Lymphocytes
by: Wei-Ting Chang, et al.
Published: (2020-10-01)

Single-Nucleus RNA-seq of Normal-Appearing Brain Regions in Relapsing-Remitting vs. Secondary Progressive Multiple Sclerosis: Implications for the Efficacy of Fingolimod
by: Yasuyuki Kihara, et al.
Published: (2022-06-01)

Fingolimod does not prevent syndecan-4 shedding from the endothelial glycocalyx in a cultured human umbilical vein endothelial cell model of vascular injury
by: Elissa M. Milford, et al.
Published: (2022-08-01)

Preclinical Evaluation of Fingolimod in Rodent Models of Stroke With Age or Atherosclerosis as Comorbidities
by: Andrea C. Diaz Diaz, et al.
Published: (2022-07-01)