Coenzyme Q10 Activates the Antioxidant Machinery and Inhibits the Inflammatory and Apoptotic Cascades Against Lead Acetate-Induced Renal Injury in Rats

Coenzyme Q10 Activates the Antioxidant Machinery and Inhibits the Inflammatory and Apoptotic Cascades Against Lead Acetate-Induced Renal Injury in Rats

The kidney is among the metabolic organs most susceptible to injury, particularly following exposure to xenobiotics and heavy metals. We aimed to explore the potential protective impacts of coenzyme Q10 (CoQ10) on lead acetate (PbAc)-induced nephrotoxicity in rats. Four experimental groups (n = 7) w...

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Bibliographic Details
Main Authors: Wafa A. AL-Megrin, Doaa Soliman, Rami B. Kassab, Dina M. Metwally, Ahmed E. Abdel Moneim, Manal F. El-Khadragy
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Physiology
Subjects:
coenzyme Q10
lead acetate
kidney
oxidative stress
inflammation
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00064/full

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