Migrasome, a novel organelle, differs from exosomes
Migrasomes, a newly discovered organelle produced by migrating cells, are vesicles with membranous structure that form on the tips and intersections of retraction fibers (RFs). These structures are released into the extracellular environment or taken up by surrounding cells, mediating the release of...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-09-01
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| Series: | Biochemistry and Biophysics Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S240558082300081X |
| _version_ | 1827794113801486336 |
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| author | Xun Tan Shujin He Fuling Wang Lei Li Wei Wang |
| author_facet | Xun Tan Shujin He Fuling Wang Lei Li Wei Wang |
| author_sort | Xun Tan |
| collection | DOAJ |
| description | Migrasomes, a newly discovered organelle produced by migrating cells, are vesicles with membranous structure that form on the tips and intersections of retraction fibers (RFs). These structures are released into the extracellular environment or taken up by surrounding cells, mediating the release of cytoplasmic contents and intercellular communication. Retractosomes, a new type of small extracellular vesicles generated from broken-off RFs, are closely related to migrasomes in their physical location and origin, but were defined later. Despite their widespread existence in cells and biological organisms, little is known about the regulatory mechanisms underlying their formation and potential function. In this review, we provide an overview of the discovery, biogenesis, distribution, and functions of migrasomes and retractosomes, as well as their differences from exosomes. |
| first_indexed | 2024-03-11T18:28:05Z |
| format | Article |
| id | doaj.art-929c4ef1a1cc48ee82bc4f4cec7d6bb0 |
| institution | Directory Open Access Journal |
| issn | 2405-5808 |
| language | English |
| last_indexed | 2024-03-11T18:28:05Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Biochemistry and Biophysics Reports |
| spelling | doaj.art-929c4ef1a1cc48ee82bc4f4cec7d6bb02023-10-13T13:54:52ZengElsevierBiochemistry and Biophysics Reports2405-58082023-09-0135101500Migrasome, a novel organelle, differs from exosomesXun Tan0Shujin He1Fuling Wang2Lei Li3Wei Wang4Department of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272029, ChinaDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272029, China; Department of Pathology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, ChinaDepartment of Obstetrics, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272029, ChinaDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272029, ChinaDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272029, China; Corresponding author.Migrasomes, a newly discovered organelle produced by migrating cells, are vesicles with membranous structure that form on the tips and intersections of retraction fibers (RFs). These structures are released into the extracellular environment or taken up by surrounding cells, mediating the release of cytoplasmic contents and intercellular communication. Retractosomes, a new type of small extracellular vesicles generated from broken-off RFs, are closely related to migrasomes in their physical location and origin, but were defined later. Despite their widespread existence in cells and biological organisms, little is known about the regulatory mechanisms underlying their formation and potential function. In this review, we provide an overview of the discovery, biogenesis, distribution, and functions of migrasomes and retractosomes, as well as their differences from exosomes.http://www.sciencedirect.com/science/article/pii/S240558082300081XOrganellesVesiclesMigrasomesRetractosomesExosomes |
| spellingShingle | Xun Tan Shujin He Fuling Wang Lei Li Wei Wang Migrasome, a novel organelle, differs from exosomes Biochemistry and Biophysics Reports Organelles Vesicles Migrasomes Retractosomes Exosomes |
| title | Migrasome, a novel organelle, differs from exosomes |
| title_full | Migrasome, a novel organelle, differs from exosomes |
| title_fullStr | Migrasome, a novel organelle, differs from exosomes |
| title_full_unstemmed | Migrasome, a novel organelle, differs from exosomes |
| title_short | Migrasome, a novel organelle, differs from exosomes |
| title_sort | migrasome a novel organelle differs from exosomes |
| topic | Organelles Vesicles Migrasomes Retractosomes Exosomes |
| url | http://www.sciencedirect.com/science/article/pii/S240558082300081X |
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