Acupuncture modulates the gut microbiota in Alzheimer’s disease: current evidence, challenges, and future opportunities
Alzheimer’s disease, one of the most severe and common neurodegenerative diseases, has no effective cure. Therefore it is crucial to explore novel and effective therapeutic targets. The gut microbiota - brain axis has been found to play a role in Alzheimer’s disease by regulating the neuro-immune an...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-03-01
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| Series: | Frontiers in Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2024.1334735/full |
| _version_ | 1797289815847206912 |
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| author | Long Yan Long Yan Hong Li Hong Li Yulin Qian Qidi Liu Qidi Liu Shan Cong Shan Cong Baomin Dou Yu Wang Meng Wang Tao Yu |
| author_facet | Long Yan Long Yan Hong Li Hong Li Yulin Qian Qidi Liu Qidi Liu Shan Cong Shan Cong Baomin Dou Yu Wang Meng Wang Tao Yu |
| author_sort | Long Yan |
| collection | DOAJ |
| description | Alzheimer’s disease, one of the most severe and common neurodegenerative diseases, has no effective cure. Therefore it is crucial to explore novel and effective therapeutic targets. The gut microbiota - brain axis has been found to play a role in Alzheimer’s disease by regulating the neuro-immune and endocrine systems. At the same time, acupuncture can modulate the gut microbiota and may impact the course of Alzheimer’s disease. In this Review, we discuss recent studies on the role of acupuncture on the gut microbiota as well current challenges and future opportunities of acupuncture as potential treatment for the prevention and treatment of Alzheimer’s disease. |
| first_indexed | 2024-03-07T19:10:33Z |
| format | Article |
| id | doaj.art-929cf78d84be4e38bc374596df13887a |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-03-07T19:10:33Z |
| publishDate | 2024-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-929cf78d84be4e38bc374596df13887a2024-03-01T04:24:03ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2024-03-011810.3389/fnins.2024.13347351334735Acupuncture modulates the gut microbiota in Alzheimer’s disease: current evidence, challenges, and future opportunitiesLong Yan0Long Yan1Hong Li2Hong Li3Yulin Qian4Qidi Liu5Qidi Liu6Shan Cong7Shan Cong8Baomin Dou9Yu Wang10Meng Wang11Tao Yu12The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Acupuncture and Moxibustion, Tianjin, ChinaThe First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Acupuncture and Moxibustion, Tianjin, ChinaThe First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaThe First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Acupuncture and Moxibustion, Tianjin, ChinaThe First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaNational Clinical Research Center for Acupuncture and Moxibustion, Tianjin, ChinaNational Clinical Research Center for Acupuncture and Moxibustion, Tianjin, ChinaThe First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaThe First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaThe First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaAlzheimer’s disease, one of the most severe and common neurodegenerative diseases, has no effective cure. Therefore it is crucial to explore novel and effective therapeutic targets. The gut microbiota - brain axis has been found to play a role in Alzheimer’s disease by regulating the neuro-immune and endocrine systems. At the same time, acupuncture can modulate the gut microbiota and may impact the course of Alzheimer’s disease. In this Review, we discuss recent studies on the role of acupuncture on the gut microbiota as well current challenges and future opportunities of acupuncture as potential treatment for the prevention and treatment of Alzheimer’s disease.https://www.frontiersin.org/articles/10.3389/fnins.2024.1334735/fullacupunctureAlzheimer’s diseasegut microbiotaprobioticsinflammation |
| spellingShingle | Long Yan Long Yan Hong Li Hong Li Yulin Qian Qidi Liu Qidi Liu Shan Cong Shan Cong Baomin Dou Yu Wang Meng Wang Tao Yu Acupuncture modulates the gut microbiota in Alzheimer’s disease: current evidence, challenges, and future opportunities Frontiers in Neuroscience acupuncture Alzheimer’s disease gut microbiota probiotics inflammation |
| title | Acupuncture modulates the gut microbiota in Alzheimer’s disease: current evidence, challenges, and future opportunities |
| title_full | Acupuncture modulates the gut microbiota in Alzheimer’s disease: current evidence, challenges, and future opportunities |
| title_fullStr | Acupuncture modulates the gut microbiota in Alzheimer’s disease: current evidence, challenges, and future opportunities |
| title_full_unstemmed | Acupuncture modulates the gut microbiota in Alzheimer’s disease: current evidence, challenges, and future opportunities |
| title_short | Acupuncture modulates the gut microbiota in Alzheimer’s disease: current evidence, challenges, and future opportunities |
| title_sort | acupuncture modulates the gut microbiota in alzheimer s disease current evidence challenges and future opportunities |
| topic | acupuncture Alzheimer’s disease gut microbiota probiotics inflammation |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2024.1334735/full |
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