Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis
Diabetic nephropathy (DN) is a common diabetic complication. Long noncoding RNAs (lncRNAs) have been identified as essential regulators in DN progression. This study is devoted to the research of lncRNA-myocardial infarction-associated transcript (MIAT) in DN.
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2021-09-01
|
| Series: | Open Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/med-2021-0328 |
| _version_ | 1818025211967045632 |
|---|---|
| author | Dong Qianlan Wang Qiong Yan Xiaohui Wang Xiaoming Li Zhenjiang Zhang Linping |
| author_facet | Dong Qianlan Wang Qiong Yan Xiaohui Wang Xiaoming Li Zhenjiang Zhang Linping |
| author_sort | Dong Qianlan |
| collection | DOAJ |
| description | Diabetic nephropathy (DN) is a common diabetic complication. Long noncoding RNAs (lncRNAs) have been identified as essential regulators in DN progression. This study is devoted to the research of lncRNA-myocardial infarction-associated transcript (MIAT) in DN. |
| first_indexed | 2024-12-10T04:12:31Z |
| format | Article |
| id | doaj.art-929d2e0dac2346f6a54c52bf927f9c6d |
| institution | Directory Open Access Journal |
| issn | 2391-5463 |
| language | English |
| last_indexed | 2024-12-10T04:12:31Z |
| publishDate | 2021-09-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj.art-929d2e0dac2346f6a54c52bf927f9c6d2022-12-22T02:02:41ZengDe GruyterOpen Medicine2391-54632021-09-011611336134910.1515/med-2021-0328Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axisDong Qianlan0Wang Qiong1Yan Xiaohui2Wang Xiaoming3Li Zhenjiang4Zhang Linping5Kidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, ChinaKidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, ChinaKidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, ChinaKidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, ChinaKidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, ChinaKidney Disease and Dialysis Center, Shaanxi Provincial People’s Hospital, Beilin District, Xi’an, Shaanxi, 710068, ChinaDiabetic nephropathy (DN) is a common diabetic complication. Long noncoding RNAs (lncRNAs) have been identified as essential regulators in DN progression. This study is devoted to the research of lncRNA-myocardial infarction-associated transcript (MIAT) in DN.https://doi.org/10.1515/med-2021-0328miatdnmir-182-5pgprc5anf-κb pathway |
| spellingShingle | Dong Qianlan Wang Qiong Yan Xiaohui Wang Xiaoming Li Zhenjiang Zhang Linping Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis Open Medicine miat dn mir-182-5p gprc5a nf-κb pathway |
| title | Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis |
| title_full | Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis |
| title_fullStr | Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis |
| title_full_unstemmed | Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis |
| title_short | Long noncoding RNA MIAT inhibits the progression of diabetic nephropathy and the activation of NF-κB pathway in high glucose-treated renal tubular epithelial cells by the miR-182-5p/GPRC5A axis |
| title_sort | long noncoding rna miat inhibits the progression of diabetic nephropathy and the activation of nf κb pathway in high glucose treated renal tubular epithelial cells by the mir 182 5p gprc5a axis |
| topic | miat dn mir-182-5p gprc5a nf-κb pathway |
| url | https://doi.org/10.1515/med-2021-0328 |
| work_keys_str_mv | AT dongqianlan longnoncodingrnamiatinhibitstheprogressionofdiabeticnephropathyandtheactivationofnfkbpathwayinhighglucosetreatedrenaltubularepithelialcellsbythemir1825pgprc5aaxis AT wangqiong longnoncodingrnamiatinhibitstheprogressionofdiabeticnephropathyandtheactivationofnfkbpathwayinhighglucosetreatedrenaltubularepithelialcellsbythemir1825pgprc5aaxis AT yanxiaohui longnoncodingrnamiatinhibitstheprogressionofdiabeticnephropathyandtheactivationofnfkbpathwayinhighglucosetreatedrenaltubularepithelialcellsbythemir1825pgprc5aaxis AT wangxiaoming longnoncodingrnamiatinhibitstheprogressionofdiabeticnephropathyandtheactivationofnfkbpathwayinhighglucosetreatedrenaltubularepithelialcellsbythemir1825pgprc5aaxis AT lizhenjiang longnoncodingrnamiatinhibitstheprogressionofdiabeticnephropathyandtheactivationofnfkbpathwayinhighglucosetreatedrenaltubularepithelialcellsbythemir1825pgprc5aaxis AT zhanglinping longnoncodingrnamiatinhibitstheprogressionofdiabeticnephropathyandtheactivationofnfkbpathwayinhighglucosetreatedrenaltubularepithelialcellsbythemir1825pgprc5aaxis |