Oxaliplatin Induced Pulmonary Fibrosis: a Case Report
Oxaliplatin is part of the standard chemotherapy regimens for treating colorectal carcinoma. Pulmonary fibrosis is a serious but rare side effect of oxaliplatin treatment, which resulted in patient death in more than half of the reported cases. The precise pathophysiological mechanism of this phe...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2020-01-01
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| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/370926 |
| Summary: | Oxaliplatin is part of the standard chemotherapy regimens for treating colorectal
carcinoma. Pulmonary fibrosis is a serious but rare side effect of oxaliplatin treatment, which resulted
in patient death in more than half of the reported cases. The precise pathophysiological mechanism of
this phenomenon has not been clarified yet. Analysis of the reported cases strongly suggests that
early diagnosis and immediate corticosteroid treatment are crucial for better prognosis. Here we report
a case of pulmonary fibrosis related to the FOLFOX regimen in a patient with early colorectal
carcinoma. |
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| ISSN: | 0353-9466 1333-9451 |