Numerical-Sampling-Functionalized Real-Time Index Regulation for Direct k-Domain Calibration in Spectral Domain Optical Coherence Tomography
An index-regulation technique functionalized by numerical sampling for direct calibration of the non-linear wavenumber (k)-domain to a linear domain in spectral domain optical coherence tomography (SD-OCT) is proposed. The objective of the developed method is to facilitate high-resolution identifica...
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| Format: | Article |
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MDPI AG
2018-09-01
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| Series: | Electronics |
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| Online Access: | http://www.mdpi.com/2079-9292/7/9/182 |
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| author | Sangyeob Han Oeon Kwon Ruchire Eranga Wijesinghe Pilun Kim Unsang Jung Jaewon Song Changho Lee Mansik Jeon Jeehyun Kim |
| author_facet | Sangyeob Han Oeon Kwon Ruchire Eranga Wijesinghe Pilun Kim Unsang Jung Jaewon Song Changho Lee Mansik Jeon Jeehyun Kim |
| author_sort | Sangyeob Han |
| collection | DOAJ |
| description | An index-regulation technique functionalized by numerical sampling for direct calibration of the non-linear wavenumber (k)-domain to a linear domain in spectral domain optical coherence tomography (SD-OCT) is proposed. The objective of the developed method is to facilitate high-resolution identification of microstructures in biomedical imaging. Subjective optical alignments caused by nonlinear sampling of interferograms in the k-domain tend to hinder depth-dependent signal-to-noise ratios (SNR) and axial resolution in SD-OCT. Moreover, the optical-laser-dependent k-domain requires constant recalibrated in accordance with each laser transition, thereby necessitating either hardware or heavy software compensations. As the key feature of the proposed method, a relatively simple software-based k-domain mask calibration technique was developed to enable real-time linear sampling of k-domain interpolations whilst facilitating image observation through use of an index-regulation technique. Moreover, it has been confirmed that dispersion can be simultaneously compensated with noise residuals generated using the proposed technique, and that use of complex numerical or hardware techniques are no longer required. Observed results, such as fall-off, SNR, and axial resolution clearly exhibit the direct impact of the proposed technique, which could help investigators rapidly achieve optical-laser-independent high-quality SD-OCT images. |
| first_indexed | 2024-04-11T13:09:25Z |
| format | Article |
| id | doaj.art-929f72062b804197aa93e3160f463f14 |
| institution | Directory Open Access Journal |
| issn | 2079-9292 |
| language | English |
| last_indexed | 2024-04-11T13:09:25Z |
| publishDate | 2018-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Electronics |
| spelling | doaj.art-929f72062b804197aa93e3160f463f142022-12-22T04:22:38ZengMDPI AGElectronics2079-92922018-09-017918210.3390/electronics7090182electronics7090182Numerical-Sampling-Functionalized Real-Time Index Regulation for Direct k-Domain Calibration in Spectral Domain Optical Coherence TomographySangyeob Han0Oeon Kwon1Ruchire Eranga Wijesinghe2Pilun Kim3Unsang Jung4Jaewon Song5Changho Lee6Mansik Jeon7Jeehyun Kim8School of Electronics Engineering, College of IT Engineering, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 41566, KoreaSchool of Electronics Engineering, College of IT Engineering, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 41566, KoreaDepartment of Biomedical Engineering, College of Engineering, Kyungil University, 50, Gamasil-gil, Hayang-eup, Gyeongsan-si, Gyeongsangbuk-do 38428, KoreaInstitute of Biomedical Engineering, School of Medicine, Kyungpook National University, 680, Gukchaebosang-ro, Jung-gu, Daegu 41944, KoreaFuture IT Innovation Laboratory, Department of Creative IT Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-ro, Nam-gu, Pohang-si, Gyeongbuk-do 37673, KoreaSchool of Electronics Engineering, College of IT Engineering, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 41566, KoreaDepartment of Nuclear Medicine, Chonnam National University Medical School & Hwasun Hospital, Hwasun 58128, KoreaSchool of Electronics Engineering, College of IT Engineering, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 41566, KoreaSchool of Electronics Engineering, College of IT Engineering, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 41566, KoreaAn index-regulation technique functionalized by numerical sampling for direct calibration of the non-linear wavenumber (k)-domain to a linear domain in spectral domain optical coherence tomography (SD-OCT) is proposed. The objective of the developed method is to facilitate high-resolution identification of microstructures in biomedical imaging. Subjective optical alignments caused by nonlinear sampling of interferograms in the k-domain tend to hinder depth-dependent signal-to-noise ratios (SNR) and axial resolution in SD-OCT. Moreover, the optical-laser-dependent k-domain requires constant recalibrated in accordance with each laser transition, thereby necessitating either hardware or heavy software compensations. As the key feature of the proposed method, a relatively simple software-based k-domain mask calibration technique was developed to enable real-time linear sampling of k-domain interpolations whilst facilitating image observation through use of an index-regulation technique. Moreover, it has been confirmed that dispersion can be simultaneously compensated with noise residuals generated using the proposed technique, and that use of complex numerical or hardware techniques are no longer required. Observed results, such as fall-off, SNR, and axial resolution clearly exhibit the direct impact of the proposed technique, which could help investigators rapidly achieve optical-laser-independent high-quality SD-OCT images.http://www.mdpi.com/2079-9292/7/9/182optical coherence tomography (OCT)Numerical samplingk-domainspectral calibration |
| spellingShingle | Sangyeob Han Oeon Kwon Ruchire Eranga Wijesinghe Pilun Kim Unsang Jung Jaewon Song Changho Lee Mansik Jeon Jeehyun Kim Numerical-Sampling-Functionalized Real-Time Index Regulation for Direct k-Domain Calibration in Spectral Domain Optical Coherence Tomography Electronics optical coherence tomography (OCT) Numerical sampling k-domain spectral calibration |
| title | Numerical-Sampling-Functionalized Real-Time Index Regulation for Direct k-Domain Calibration in Spectral Domain Optical Coherence Tomography |
| title_full | Numerical-Sampling-Functionalized Real-Time Index Regulation for Direct k-Domain Calibration in Spectral Domain Optical Coherence Tomography |
| title_fullStr | Numerical-Sampling-Functionalized Real-Time Index Regulation for Direct k-Domain Calibration in Spectral Domain Optical Coherence Tomography |
| title_full_unstemmed | Numerical-Sampling-Functionalized Real-Time Index Regulation for Direct k-Domain Calibration in Spectral Domain Optical Coherence Tomography |
| title_short | Numerical-Sampling-Functionalized Real-Time Index Regulation for Direct k-Domain Calibration in Spectral Domain Optical Coherence Tomography |
| title_sort | numerical sampling functionalized real time index regulation for direct k domain calibration in spectral domain optical coherence tomography |
| topic | optical coherence tomography (OCT) Numerical sampling k-domain spectral calibration |
| url | http://www.mdpi.com/2079-9292/7/9/182 |
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