Neuroprotective mechanisms of Asiatic acid
Asiatic acid (AA) is the most crucial component of Asiaticoside in many edible and medicinal plants. It has diverse biological activities such as anti-inflammatory, antioxidant, anti-infective, and anti-tumor. Additionally, AA has been intensively studied in the last decades. It has shown great pote...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-05-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023030608 |
| _version_ | 1827937458716672000 |
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| author | Liuyun Ding Tiantian Liu Jin Ma |
| author_facet | Liuyun Ding Tiantian Liu Jin Ma |
| author_sort | Liuyun Ding |
| collection | DOAJ |
| description | Asiatic acid (AA) is the most crucial component of Asiaticoside in many edible and medicinal plants. It has diverse biological activities such as anti-inflammatory, antioxidant, anti-infective, and anti-tumor. Additionally, AA has been intensively studied in the last decades. It has shown great potential in the treatment of various neurological diseases such as spinal cord injury (SCI), cerebral ischemia, epilepsy, traumatic brain injury (TBI), neural tumors, Alzheimer's disease (AD), and Parkinson's disease (PD). Moreover, AA provides pertinent data for neuroprotective signaling pathways, and its substantial neuroprotective ability makes it a novel candidate for developing drugs that target the central nervous system. |
| first_indexed | 2024-03-13T08:25:55Z |
| format | Article |
| id | doaj.art-929f7e31833246f1aa612f2f04dc79da |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-13T08:25:55Z |
| publishDate | 2023-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-929f7e31833246f1aa612f2f04dc79da2023-05-31T04:45:46ZengElsevierHeliyon2405-84402023-05-0195e15853Neuroprotective mechanisms of Asiatic acidLiuyun Ding0Tiantian Liu1Jin Ma2Department of Emergency Medicine, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, 215300, ChinaShanghai Seventh's People's Hospital, An Affiliate of Shanghai University of Traditional Chinese Medicine, Shanghai, 200137, ChinaDepartment of Emergency Medicine, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, 215300, China; Corresponding author. Department of Emergency Medicine, Affiliated Kunshan Hospital of Jiangsu University, No. 91 Qianjin West Road, Kunshan, 215300, China.Asiatic acid (AA) is the most crucial component of Asiaticoside in many edible and medicinal plants. It has diverse biological activities such as anti-inflammatory, antioxidant, anti-infective, and anti-tumor. Additionally, AA has been intensively studied in the last decades. It has shown great potential in the treatment of various neurological diseases such as spinal cord injury (SCI), cerebral ischemia, epilepsy, traumatic brain injury (TBI), neural tumors, Alzheimer's disease (AD), and Parkinson's disease (PD). Moreover, AA provides pertinent data for neuroprotective signaling pathways, and its substantial neuroprotective ability makes it a novel candidate for developing drugs that target the central nervous system.http://www.sciencedirect.com/science/article/pii/S2405844023030608Asiatic acidNeuroprotectionSignaling pathwaysMolecular targetsCentral nervous system |
| spellingShingle | Liuyun Ding Tiantian Liu Jin Ma Neuroprotective mechanisms of Asiatic acid Heliyon Asiatic acid Neuroprotection Signaling pathways Molecular targets Central nervous system |
| title | Neuroprotective mechanisms of Asiatic acid |
| title_full | Neuroprotective mechanisms of Asiatic acid |
| title_fullStr | Neuroprotective mechanisms of Asiatic acid |
| title_full_unstemmed | Neuroprotective mechanisms of Asiatic acid |
| title_short | Neuroprotective mechanisms of Asiatic acid |
| title_sort | neuroprotective mechanisms of asiatic acid |
| topic | Asiatic acid Neuroprotection Signaling pathways Molecular targets Central nervous system |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023030608 |
| work_keys_str_mv | AT liuyunding neuroprotectivemechanismsofasiaticacid AT tiantianliu neuroprotectivemechanismsofasiaticacid AT jinma neuroprotectivemechanismsofasiaticacid |