Drug Combination of Ciprofloxacin and Polymyxin B for the Treatment of Multidrug–Resistant <i>Acinetobacter baumannii</i> Infections: A Drug Pair Limiting the Development of Resistance

Drug Combination of Ciprofloxacin and Polymyxin B for the Treatment of Multidrug–Resistant <i>Acinetobacter baumannii</i> Infections: A Drug Pair Limiting the Development of Resistance

Polymyxins are considered as last–resort antibiotics to treat infections caused by <i>Acinetobacter baumannii</i>. However, there are increasing reports of resistance in <i>A. baumannii</i> to polymyxins. In this study, inhalable combinational dry powders consisting of ciprof...

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Bibliographic Details
Main Authors: Junwei Wang, Marc Stegger, Arshnee Moodley, Mingshi Yang
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
drug combination
inhalable dry powders
resistance development
synergistic effect
Online Access:https://www.mdpi.com/1999-4923/15/3/720

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