Auditory neuropathy spectrum disorder (ANSD): a distortion product otoacoustic emissions (DPOAEs) study
Abstract Background Auditory neuropathy spectrum disorder (ANSD) is characterized by normal OHCs function as shown by intact cochlear microphonics (CMs) and/or otoacoustic emissions (OAEs); absent or grossly abnormal auditory brainstem responses (ABRs) and absent middle ear muscle reflexes. This stu...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2023-02-01
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| Series: | The Egyptian Journal of Otolaryngology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43163-023-00395-2 |
| _version_ | 1827267293039558656 |
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| author | Takwa Gabr Mona A. Elakkad |
| author_facet | Takwa Gabr Mona A. Elakkad |
| author_sort | Takwa Gabr |
| collection | DOAJ |
| description | Abstract Background Auditory neuropathy spectrum disorder (ANSD) is characterized by normal OHCs function as shown by intact cochlear microphonics (CMs) and/or otoacoustic emissions (OAEs); absent or grossly abnormal auditory brainstem responses (ABRs) and absent middle ear muscle reflexes. This study is designed to address whether the input/output function of distortion product OAEs (DPOAEs I/O) in ANSD patients is similar or different from normal hearing subjects. This work included 2 groups: control group (GI) composed of 20 normal hearing subjects and study group (GII) consisted of 20 patients with ANSD. All cases were subjected to basic audiological evaluation, DPOAEs I/O function recorded at four frequencies of 2f1-f2 and 5 intensity levels of L1 and L2. Results DPOAEs amplitudes were significantly higher in ANSD group when compared with control. The pattern of DPOAEs I/O function was different in ANSD and it was dependent on the frequency and intensity of the stimulus. Conclusions Despite normal DPOAEs recordings in ANSD patients, their amplitudes and DP I/O function are different from that of normal hearing subjects. This finding suggested different OHC pattern of activity in ANSD patients. |
| first_indexed | 2024-04-09T23:13:15Z |
| format | Article |
| id | doaj.art-92a17e25d5a2418d9bcd0d6b2d1c31df |
| institution | Directory Open Access Journal |
| issn | 2090-8539 |
| language | English |
| last_indexed | 2025-03-22T04:31:26Z |
| publishDate | 2023-02-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Otolaryngology |
| spelling | doaj.art-92a17e25d5a2418d9bcd0d6b2d1c31df2024-04-28T03:45:13ZengSpringerOpenThe Egyptian Journal of Otolaryngology2090-85392023-02-013911810.1186/s43163-023-00395-2Auditory neuropathy spectrum disorder (ANSD): a distortion product otoacoustic emissions (DPOAEs) studyTakwa Gabr0Mona A. Elakkad1Otolaryngology Department, Faculty of Medicine, Kafrelsheikh UniversityOtolaryngology Department, Faculty of Medicine, Fayoum UniversityAbstract Background Auditory neuropathy spectrum disorder (ANSD) is characterized by normal OHCs function as shown by intact cochlear microphonics (CMs) and/or otoacoustic emissions (OAEs); absent or grossly abnormal auditory brainstem responses (ABRs) and absent middle ear muscle reflexes. This study is designed to address whether the input/output function of distortion product OAEs (DPOAEs I/O) in ANSD patients is similar or different from normal hearing subjects. This work included 2 groups: control group (GI) composed of 20 normal hearing subjects and study group (GII) consisted of 20 patients with ANSD. All cases were subjected to basic audiological evaluation, DPOAEs I/O function recorded at four frequencies of 2f1-f2 and 5 intensity levels of L1 and L2. Results DPOAEs amplitudes were significantly higher in ANSD group when compared with control. The pattern of DPOAEs I/O function was different in ANSD and it was dependent on the frequency and intensity of the stimulus. Conclusions Despite normal DPOAEs recordings in ANSD patients, their amplitudes and DP I/O function are different from that of normal hearing subjects. This finding suggested different OHC pattern of activity in ANSD patients.https://doi.org/10.1186/s43163-023-00395-2Auditory perceptual disordersAuditory neuropathy spectrum disorderCochleaDistorted hearing |
| spellingShingle | Takwa Gabr Mona A. Elakkad Auditory neuropathy spectrum disorder (ANSD): a distortion product otoacoustic emissions (DPOAEs) study The Egyptian Journal of Otolaryngology Auditory perceptual disorders Auditory neuropathy spectrum disorder Cochlea Distorted hearing |
| title | Auditory neuropathy spectrum disorder (ANSD): a distortion product otoacoustic emissions (DPOAEs) study |
| title_full | Auditory neuropathy spectrum disorder (ANSD): a distortion product otoacoustic emissions (DPOAEs) study |
| title_fullStr | Auditory neuropathy spectrum disorder (ANSD): a distortion product otoacoustic emissions (DPOAEs) study |
| title_full_unstemmed | Auditory neuropathy spectrum disorder (ANSD): a distortion product otoacoustic emissions (DPOAEs) study |
| title_short | Auditory neuropathy spectrum disorder (ANSD): a distortion product otoacoustic emissions (DPOAEs) study |
| title_sort | auditory neuropathy spectrum disorder ansd a distortion product otoacoustic emissions dpoaes study |
| topic | Auditory perceptual disorders Auditory neuropathy spectrum disorder Cochlea Distorted hearing |
| url | https://doi.org/10.1186/s43163-023-00395-2 |
| work_keys_str_mv | AT takwagabr auditoryneuropathyspectrumdisorderansdadistortionproductotoacousticemissionsdpoaesstudy AT monaaelakkad auditoryneuropathyspectrumdisorderansdadistortionproductotoacousticemissionsdpoaesstudy |