Management of Cerebral Herniation Secondary to Lead Encephalopathy: A Case Report
BackgroundAdult lead encephalopathy is a rare but critical condition to recognize in modern healthcare settings. Few reports have described the medical and neurosurgical management of severe adult lead encephalopathy.Case PresentationA 22 year old woman presented with severe headache, anemia, vomiti...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-05-01
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| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.893767/full |
| _version_ | 1811340175335227392 |
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| author | Somnath Das Felicia Hataway Hunter S. Boudreau Yasaman Alam Jordan A. George William Rushton Sukhshant Atti Manmeet Kaur Marshall T. Holland |
| author_facet | Somnath Das Felicia Hataway Hunter S. Boudreau Yasaman Alam Jordan A. George William Rushton Sukhshant Atti Manmeet Kaur Marshall T. Holland |
| author_sort | Somnath Das |
| collection | DOAJ |
| description | BackgroundAdult lead encephalopathy is a rare but critical condition to recognize in modern healthcare settings. Few reports have described the medical and neurosurgical management of severe adult lead encephalopathy.Case PresentationA 22 year old woman presented with severe headache, anemia, vomiting, 40-lb weight loss, and constipation. At the time of presentation, she had extensive colonic radiopaque material and a serum lead concentration of 87 mcg/dl (normal <10). She rapidly developed anisocoria requiring emergent ventriculostomy insertion. Following CSF diversion, ICP mitigation, and lead chelation, she considerably improved in <2 weeks.ConclusionWe report one of the few instances of successful surgical and medical management of adult lead encephalopathy. Dedicated neurocritical care and neurosurgical teams are necessary in conjunction with toxicology in order to manage the advanced sequalae of severe lead poisoning. |
| first_indexed | 2024-04-13T18:37:13Z |
| format | Article |
| id | doaj.art-92a2050a1eb24bfebb7e4ed4d94a2e5b |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-13T18:37:13Z |
| publishDate | 2022-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-92a2050a1eb24bfebb7e4ed4d94a2e5b2022-12-22T02:34:50ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-05-011310.3389/fneur.2022.893767893767Management of Cerebral Herniation Secondary to Lead Encephalopathy: A Case ReportSomnath Das0Felicia Hataway1Hunter S. Boudreau2Yasaman Alam3Jordan A. George4William Rushton5Sukhshant Atti6Manmeet Kaur7Marshall T. Holland8Department of Neurosurgery, University of Alabama Birmingham, Birmingham, AL, United StatesDepartment of Neurology, University of Alabama Birmingham, Birmingham, AL, United StatesSchool of Medicine, University of Alabama Birmingham, Birmingham, AL, United StatesDepartment of Neurosurgery, University of Alabama Birmingham, Birmingham, AL, United StatesSchool of Medicine, University of Alabama Birmingham, Birmingham, AL, United StatesOffice of Toxicology, University of Alabama Birmingham, Birmingham, AL, United StatesOffice of Toxicology, University of Alabama Birmingham, Birmingham, AL, United StatesDepartment of Neurology, University of Alabama Birmingham, Birmingham, AL, United StatesDepartment of Neurosurgery, University of Alabama Birmingham, Birmingham, AL, United StatesBackgroundAdult lead encephalopathy is a rare but critical condition to recognize in modern healthcare settings. Few reports have described the medical and neurosurgical management of severe adult lead encephalopathy.Case PresentationA 22 year old woman presented with severe headache, anemia, vomiting, 40-lb weight loss, and constipation. At the time of presentation, she had extensive colonic radiopaque material and a serum lead concentration of 87 mcg/dl (normal <10). She rapidly developed anisocoria requiring emergent ventriculostomy insertion. Following CSF diversion, ICP mitigation, and lead chelation, she considerably improved in <2 weeks.ConclusionWe report one of the few instances of successful surgical and medical management of adult lead encephalopathy. Dedicated neurocritical care and neurosurgical teams are necessary in conjunction with toxicology in order to manage the advanced sequalae of severe lead poisoning.https://www.frontiersin.org/articles/10.3389/fneur.2022.893767/fulllead encephalopathyintracranial pressureventriculostomylead toxicityneurocritical care |
| spellingShingle | Somnath Das Felicia Hataway Hunter S. Boudreau Yasaman Alam Jordan A. George William Rushton Sukhshant Atti Manmeet Kaur Marshall T. Holland Management of Cerebral Herniation Secondary to Lead Encephalopathy: A Case Report Frontiers in Neurology lead encephalopathy intracranial pressure ventriculostomy lead toxicity neurocritical care |
| title | Management of Cerebral Herniation Secondary to Lead Encephalopathy: A Case Report |
| title_full | Management of Cerebral Herniation Secondary to Lead Encephalopathy: A Case Report |
| title_fullStr | Management of Cerebral Herniation Secondary to Lead Encephalopathy: A Case Report |
| title_full_unstemmed | Management of Cerebral Herniation Secondary to Lead Encephalopathy: A Case Report |
| title_short | Management of Cerebral Herniation Secondary to Lead Encephalopathy: A Case Report |
| title_sort | management of cerebral herniation secondary to lead encephalopathy a case report |
| topic | lead encephalopathy intracranial pressure ventriculostomy lead toxicity neurocritical care |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.893767/full |
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