Altered Resting-State EEG Microstate in Idiopathic Sudden Sensorineural Hearing Loss Patients With Tinnitus
In order to clarify the central reorganization in acute period of hearing loss, this study explored the aberrant dynamics of electroencephalogram (EEG) microstates and the correlations with the features of idiopathic sudden sensorineural hearing loss (ISSNHL) and tinnitus. We used high-density EEG w...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-05-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fnins.2019.00443/full |
| _version_ | 1819146107716894720 |
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| author | Yuexin Cai Yuexin Cai Suijun Chen Suijun Chen Yanhong Chen Yanhong Chen Jiahong Li Jiahong Li Chang-Dong Wang Fei Zhao Fei Zhao Cai-Ping Dang Cai-Ping Dang Jianheng Liang Nannan He Maojin Liang Maojin Liang Yiqing Zheng Yiqing Zheng |
| author_facet | Yuexin Cai Yuexin Cai Suijun Chen Suijun Chen Yanhong Chen Yanhong Chen Jiahong Li Jiahong Li Chang-Dong Wang Fei Zhao Fei Zhao Cai-Ping Dang Cai-Ping Dang Jianheng Liang Nannan He Maojin Liang Maojin Liang Yiqing Zheng Yiqing Zheng |
| author_sort | Yuexin Cai |
| collection | DOAJ |
| description | In order to clarify the central reorganization in acute period of hearing loss, this study explored the aberrant dynamics of electroencephalogram (EEG) microstates and the correlations with the features of idiopathic sudden sensorineural hearing loss (ISSNHL) and tinnitus. We used high-density EEG with 128 channels to investigate alterations in microstate parameters between 25 ISSNHL patients with tinnitus and 27 healthy subjects. This study also explored the associations between microstate characteristics and tinnitus features. Microstates were clustered into four categories. There was a reduced presence of microstate A in amplitude, coverage, lifespan, frequency and an increased presence of microstate B in frequency in ISSNHL patients with tinnitus. According to the syntax analysis, a reduced transition from microstate C to microstate A and an increased transition from microstate C to microstate B were found in ISSNHL subjects. In addition, the significant negative correlations were found between Tinnitus Handicap Inventory (THI) scores and frequency of microstate A as well as between THI scores and the probability of transition from microstate D to microstate A. While THI was positively correlated with the transition probability from microstate D to microstate B. To sum up, the significant differences in the characteristics of resting-state EEG microstates were found between ISSNHL subjects with tinnitus and healthy controls. This study suggests that the alterations of central neural networks occur in acute stage of hearing loss and tinnitus. And EEG microstate may be considered as a useful tool to study the whole brain network in ISSNHL patients. |
| first_indexed | 2024-12-22T13:08:40Z |
| format | Article |
| id | doaj.art-92abbe807d9f4349af7dad5dbc615e0b |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-12-22T13:08:40Z |
| publishDate | 2019-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-92abbe807d9f4349af7dad5dbc615e0b2022-12-21T18:24:48ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2019-05-011310.3389/fnins.2019.00443454613Altered Resting-State EEG Microstate in Idiopathic Sudden Sensorineural Hearing Loss Patients With TinnitusYuexin Cai0Yuexin Cai1Suijun Chen2Suijun Chen3Yanhong Chen4Yanhong Chen5Jiahong Li6Jiahong Li7Chang-Dong Wang8Fei Zhao9Fei Zhao10Cai-Ping Dang11Cai-Ping Dang12Jianheng Liang13Nannan He14Maojin Liang15Maojin Liang16Yiqing Zheng17Yiqing Zheng18Department of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaInstitute of Hearing and Speech-Language Science, Sun Yat-sen University, Guangzhou, ChinaDepartment of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaInstitute of Hearing and Speech-Language Science, Sun Yat-sen University, Guangzhou, ChinaDepartment of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaInstitute of Hearing and Speech-Language Science, Sun Yat-sen University, Guangzhou, ChinaDepartment of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaInstitute of Hearing and Speech-Language Science, Sun Yat-sen University, Guangzhou, ChinaSchool of Data and Computer Science, Sun Yat-sen University, Guangzhou, ChinaDepartment of Speech Language Therapy and Hearing Science, Cardiff Metropolitan University, Cardiff, United KingdomDepartment of Hearing and Speech Science, Xinhua College, Sun Yat-sen University, Guangzhou, ChinaAffiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaDepartment of Psychology, Guangzhou Medical University, Guangzhou, ChinaCollege of Mathematics and Informatics, South China Agricultural University, Guangzhou, ChinaCollege of Mathematics and Informatics, South China Agricultural University, Guangzhou, ChinaDepartment of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaInstitute of Hearing and Speech-Language Science, Sun Yat-sen University, Guangzhou, ChinaDepartment of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, ChinaInstitute of Hearing and Speech-Language Science, Sun Yat-sen University, Guangzhou, ChinaIn order to clarify the central reorganization in acute period of hearing loss, this study explored the aberrant dynamics of electroencephalogram (EEG) microstates and the correlations with the features of idiopathic sudden sensorineural hearing loss (ISSNHL) and tinnitus. We used high-density EEG with 128 channels to investigate alterations in microstate parameters between 25 ISSNHL patients with tinnitus and 27 healthy subjects. This study also explored the associations between microstate characteristics and tinnitus features. Microstates were clustered into four categories. There was a reduced presence of microstate A in amplitude, coverage, lifespan, frequency and an increased presence of microstate B in frequency in ISSNHL patients with tinnitus. According to the syntax analysis, a reduced transition from microstate C to microstate A and an increased transition from microstate C to microstate B were found in ISSNHL subjects. In addition, the significant negative correlations were found between Tinnitus Handicap Inventory (THI) scores and frequency of microstate A as well as between THI scores and the probability of transition from microstate D to microstate A. While THI was positively correlated with the transition probability from microstate D to microstate B. To sum up, the significant differences in the characteristics of resting-state EEG microstates were found between ISSNHL subjects with tinnitus and healthy controls. This study suggests that the alterations of central neural networks occur in acute stage of hearing loss and tinnitus. And EEG microstate may be considered as a useful tool to study the whole brain network in ISSNHL patients.https://www.frontiersin.org/article/10.3389/fnins.2019.00443/fullEEGmicrostatetinnitusISSNHLmechanism |
| spellingShingle | Yuexin Cai Yuexin Cai Suijun Chen Suijun Chen Yanhong Chen Yanhong Chen Jiahong Li Jiahong Li Chang-Dong Wang Fei Zhao Fei Zhao Cai-Ping Dang Cai-Ping Dang Jianheng Liang Nannan He Maojin Liang Maojin Liang Yiqing Zheng Yiqing Zheng Altered Resting-State EEG Microstate in Idiopathic Sudden Sensorineural Hearing Loss Patients With Tinnitus Frontiers in Neuroscience EEG microstate tinnitus ISSNHL mechanism |
| title | Altered Resting-State EEG Microstate in Idiopathic Sudden Sensorineural Hearing Loss Patients With Tinnitus |
| title_full | Altered Resting-State EEG Microstate in Idiopathic Sudden Sensorineural Hearing Loss Patients With Tinnitus |
| title_fullStr | Altered Resting-State EEG Microstate in Idiopathic Sudden Sensorineural Hearing Loss Patients With Tinnitus |
| title_full_unstemmed | Altered Resting-State EEG Microstate in Idiopathic Sudden Sensorineural Hearing Loss Patients With Tinnitus |
| title_short | Altered Resting-State EEG Microstate in Idiopathic Sudden Sensorineural Hearing Loss Patients With Tinnitus |
| title_sort | altered resting state eeg microstate in idiopathic sudden sensorineural hearing loss patients with tinnitus |
| topic | EEG microstate tinnitus ISSNHL mechanism |
| url | https://www.frontiersin.org/article/10.3389/fnins.2019.00443/full |
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