Multiscale Sample Entropy of Cardiovascular Signals: Does the Choice between Fixed- or Varying-Tolerance among Scales Influence Its Evaluation and Interpretation?
Multiscale entropy (MSE) quantifies the cardiovascular complexity evaluating Sample Entropy (SampEn) on coarse-grained series at increasing scales τ. Two approaches exist, one using a fixed tolerance r at all scales (MSEFT), the other a varying tolerance r(τ) adjusted following the standard-deviatio...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-11-01
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| Series: | Entropy |
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| Online Access: | https://www.mdpi.com/1099-4300/19/11/590 |
| _version_ | 1811299928976130048 |
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| author | Paolo Castiglioni Paolo Coruzzi Matteo Bini Gianfranco Parati Andrea Faini |
| author_facet | Paolo Castiglioni Paolo Coruzzi Matteo Bini Gianfranco Parati Andrea Faini |
| author_sort | Paolo Castiglioni |
| collection | DOAJ |
| description | Multiscale entropy (MSE) quantifies the cardiovascular complexity evaluating Sample Entropy (SampEn) on coarse-grained series at increasing scales τ. Two approaches exist, one using a fixed tolerance r at all scales (MSEFT), the other a varying tolerance r(τ) adjusted following the standard-deviation changes after coarse graining (MSEVT). The aim of this study is to clarify how the choice between MSEFT and MSEVT influences quantification and interpretation of cardiovascular MSE, and whether it affects some signals more than others. To achieve this aim, we considered 2-h long beat-by-beat recordings of inter-beat intervals and of systolic and diastolic blood pressures in male (N = 42) and female (N = 42) healthy volunteers. We compared MSE estimated with fixed and varying tolerances, and evaluated whether the choice between MSEFT and MSEVT estimators influence quantification and interpretation of sex-related differences. We found substantial discrepancies between MSEFT and MSEVT results, related to the degree of correlation among samples and more important for heart rate than for blood pressure; moreover the choice between MSEFT and MSEVT may influence the interpretation of gender differences for MSE of heart rate. We conclude that studies on cardiovascular complexity should carefully choose between fixed- or varying-tolerance estimators, particularly when evaluating MSE of heart rate. |
| first_indexed | 2024-04-13T06:44:01Z |
| format | Article |
| id | doaj.art-92ad8440e96d48509081ba7c755b55d7 |
| institution | Directory Open Access Journal |
| issn | 1099-4300 |
| language | English |
| last_indexed | 2024-04-13T06:44:01Z |
| publishDate | 2017-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Entropy |
| spelling | doaj.art-92ad8440e96d48509081ba7c755b55d72022-12-22T02:57:39ZengMDPI AGEntropy1099-43002017-11-01191159010.3390/e19110590e19110590Multiscale Sample Entropy of Cardiovascular Signals: Does the Choice between Fixed- or Varying-Tolerance among Scales Influence Its Evaluation and Interpretation?Paolo Castiglioni0Paolo Coruzzi1Matteo Bini2Gianfranco Parati3Andrea Faini4IRCCS Fondazione Don C. Gnocchi, 20148 Milan, ItalyDepartment of Medicine and Surgery, University of Parma, 43121 Parma, ItalyDepartment of Medicine and Surgery, University of Parma, 43121 Parma, ItalyDepartment of Cardiology, Istituto Auxologico Italiano, 20149 Milan, ItalyDepartment of Cardiology, Istituto Auxologico Italiano, 20149 Milan, ItalyMultiscale entropy (MSE) quantifies the cardiovascular complexity evaluating Sample Entropy (SampEn) on coarse-grained series at increasing scales τ. Two approaches exist, one using a fixed tolerance r at all scales (MSEFT), the other a varying tolerance r(τ) adjusted following the standard-deviation changes after coarse graining (MSEVT). The aim of this study is to clarify how the choice between MSEFT and MSEVT influences quantification and interpretation of cardiovascular MSE, and whether it affects some signals more than others. To achieve this aim, we considered 2-h long beat-by-beat recordings of inter-beat intervals and of systolic and diastolic blood pressures in male (N = 42) and female (N = 42) healthy volunteers. We compared MSE estimated with fixed and varying tolerances, and evaluated whether the choice between MSEFT and MSEVT estimators influence quantification and interpretation of sex-related differences. We found substantial discrepancies between MSEFT and MSEVT results, related to the degree of correlation among samples and more important for heart rate than for blood pressure; moreover the choice between MSEFT and MSEVT may influence the interpretation of gender differences for MSE of heart rate. We conclude that studies on cardiovascular complexity should carefully choose between fixed- or varying-tolerance estimators, particularly when evaluating MSE of heart rate.https://www.mdpi.com/1099-4300/19/11/590SampEnheart rateblood pressuregender |
| spellingShingle | Paolo Castiglioni Paolo Coruzzi Matteo Bini Gianfranco Parati Andrea Faini Multiscale Sample Entropy of Cardiovascular Signals: Does the Choice between Fixed- or Varying-Tolerance among Scales Influence Its Evaluation and Interpretation? Entropy SampEn heart rate blood pressure gender |
| title | Multiscale Sample Entropy of Cardiovascular Signals: Does the Choice between Fixed- or Varying-Tolerance among Scales Influence Its Evaluation and Interpretation? |
| title_full | Multiscale Sample Entropy of Cardiovascular Signals: Does the Choice between Fixed- or Varying-Tolerance among Scales Influence Its Evaluation and Interpretation? |
| title_fullStr | Multiscale Sample Entropy of Cardiovascular Signals: Does the Choice between Fixed- or Varying-Tolerance among Scales Influence Its Evaluation and Interpretation? |
| title_full_unstemmed | Multiscale Sample Entropy of Cardiovascular Signals: Does the Choice between Fixed- or Varying-Tolerance among Scales Influence Its Evaluation and Interpretation? |
| title_short | Multiscale Sample Entropy of Cardiovascular Signals: Does the Choice between Fixed- or Varying-Tolerance among Scales Influence Its Evaluation and Interpretation? |
| title_sort | multiscale sample entropy of cardiovascular signals does the choice between fixed or varying tolerance among scales influence its evaluation and interpretation |
| topic | SampEn heart rate blood pressure gender |
| url | https://www.mdpi.com/1099-4300/19/11/590 |
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