Chemoprevention of Lung Cancer with a Combination of Mitochondria-Targeted Compounds

Chemoprevention of Lung Cancer with a Combination of Mitochondria-Targeted Compounds

Combined treatment targeting mitochondria may improve the efficacy of lung cancer chemoprevention. Here, mitochondria-targeted honokiol (Mito-HNK), an inhibitor of mitochondrial complex I and STAT3 phosphorylation, and mitochondria-targeted lonidamine (Mito-LND), an inhibitor of mitochondrial comple...

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Bibliographic Details
Main Authors: Qi Zhang, Donghai Xiong, Jing Pan, Yian Wang, Micael Hardy, Balaraman Kalyanaraman, Ming You
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
mitochondria-targeted honokiol
mitochondria-targeted lonidamine
mitochondrial bioenergetics
lung cancer
single-cell RNA sequencing
Online Access:https://www.mdpi.com/2072-6694/14/10/2538

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