Cardiac myxoma: The influence of preoperative clinical presentation and surgical technique on late outcome
Introduction Cardiac myxomas are the most frequent primary tumors of the heart in adults, and they can be found in each of four cardiac chambers. Although biologically benign, due to their unfavorable localization, myxomas are considered "functionally malignant" tumors. Diagnosis of cardia...
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| Format: | Article |
| Language: | English |
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Serbian Medical Society
2007-01-01
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| Series: | Srpski Arhiv za Celokupno Lekarstvo |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0370-8179/2007/0370-81790708401M.pdf |
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| author | Mikić Aleksandar Obrenović-Kirćanski Biljana Kočica Mladen Vraneš Mile Lačković Vesna Velinović Miloš Marković Miroslav Kovačević Nataša Đukić Petar |
| author_facet | Mikić Aleksandar Obrenović-Kirćanski Biljana Kočica Mladen Vraneš Mile Lačković Vesna Velinović Miloš Marković Miroslav Kovačević Nataša Đukić Petar |
| author_sort | Mikić Aleksandar |
| collection | DOAJ |
| description | Introduction Cardiac myxomas are the most frequent primary tumors of the heart in adults, and they can be found in each of four cardiac chambers. Although biologically benign, due to their unfavorable localization, myxomas are considered "functionally malignant" tumors. Diagnosis of cardiac myxoma necessitates surgical treatment. Objective To analyze: 1) the influence of localization, size and consistency of cardiac myxomas on preoperative symptomatology; 2) the influence of different surgical techniques (left, right, biatrial approach, tumor basis solving) on early, and late outcomes. Method From 1982 to 2000, at the Institute for Cardiovascular Diseases, Clinical Center of Serbia, there were 46 patients with cardiac myxomas operated on, 67.4% of them women, mean age 47.1±16.3 years. The diagnosis was made according to clinical presentation, electrocardiographic and echocardiographic examinations and cardiac catheterization. Follow-up period was 4-18 (mean 7.8) years. Results In 41 (89.1%) patients, myxoma was localized in the left, while in 5 (10.9%), it was found in the right atrium. Average size was 5.8×3.8 cm (range: 1×1 cm to 9×8 cm) and 6×4 cm (range: 3×2 cm to 9×5 cm) for the left and right atrial myxomas, respectively. A racemous form predominated in the left (82.6%) and globous in the right (80%) atrium. Fatigue was the most common general (84.8%) and dyspnoea the most common cardiologic symptom (73.9%). Preoperative embolic events were present in 8 patients (4 pulmonary, 4 systemic). In our series: 1) different localization, size and consistency had no influence on the preoperative symptomatology; 2) surgical treatment applied, regardless of different approaches and basis solving, resulted in excellent functional improvements (63.1% patients in NYHA III and IV class preoperatively vs. 6.7% patients postoperatively) and had no influence on new postoperative rhythm disturbances (8.7% patients preoperatively vs. 24.4% patients postoperatively); 3) early (97.8%), and late survival rates (91.3%) were excellent; 4) there were no relapses during the follow-up period. Conclusion Localization, size and consistency had no influence on the preoperative symptomatology. Excellent survival rate with significant functional improvement, rare postoperative complications and no recurrences, justify the applied strategies of surgical approach and tumor basis solving in our series. |
| first_indexed | 2024-12-19T10:40:41Z |
| format | Article |
| id | doaj.art-92b08d234c894f77a438f2360af827d3 |
| institution | Directory Open Access Journal |
| issn | 0370-8179 |
| language | English |
| last_indexed | 2024-12-19T10:40:41Z |
| publishDate | 2007-01-01 |
| publisher | Serbian Medical Society |
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| series | Srpski Arhiv za Celokupno Lekarstvo |
| spelling | doaj.art-92b08d234c894f77a438f2360af827d32022-12-21T20:25:27ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792007-01-011357-840140610.2298/SARH0708401MCardiac myxoma: The influence of preoperative clinical presentation and surgical technique on late outcomeMikić AleksandarObrenović-Kirćanski BiljanaKočica MladenVraneš MileLačković VesnaVelinović MilošMarković MiroslavKovačević NatašaĐukić PetarIntroduction Cardiac myxomas are the most frequent primary tumors of the heart in adults, and they can be found in each of four cardiac chambers. Although biologically benign, due to their unfavorable localization, myxomas are considered "functionally malignant" tumors. Diagnosis of cardiac myxoma necessitates surgical treatment. Objective To analyze: 1) the influence of localization, size and consistency of cardiac myxomas on preoperative symptomatology; 2) the influence of different surgical techniques (left, right, biatrial approach, tumor basis solving) on early, and late outcomes. Method From 1982 to 2000, at the Institute for Cardiovascular Diseases, Clinical Center of Serbia, there were 46 patients with cardiac myxomas operated on, 67.4% of them women, mean age 47.1±16.3 years. The diagnosis was made according to clinical presentation, electrocardiographic and echocardiographic examinations and cardiac catheterization. Follow-up period was 4-18 (mean 7.8) years. Results In 41 (89.1%) patients, myxoma was localized in the left, while in 5 (10.9%), it was found in the right atrium. Average size was 5.8×3.8 cm (range: 1×1 cm to 9×8 cm) and 6×4 cm (range: 3×2 cm to 9×5 cm) for the left and right atrial myxomas, respectively. A racemous form predominated in the left (82.6%) and globous in the right (80%) atrium. Fatigue was the most common general (84.8%) and dyspnoea the most common cardiologic symptom (73.9%). Preoperative embolic events were present in 8 patients (4 pulmonary, 4 systemic). In our series: 1) different localization, size and consistency had no influence on the preoperative symptomatology; 2) surgical treatment applied, regardless of different approaches and basis solving, resulted in excellent functional improvements (63.1% patients in NYHA III and IV class preoperatively vs. 6.7% patients postoperatively) and had no influence on new postoperative rhythm disturbances (8.7% patients preoperatively vs. 24.4% patients postoperatively); 3) early (97.8%), and late survival rates (91.3%) were excellent; 4) there were no relapses during the follow-up period. Conclusion Localization, size and consistency had no influence on the preoperative symptomatology. Excellent survival rate with significant functional improvement, rare postoperative complications and no recurrences, justify the applied strategies of surgical approach and tumor basis solving in our series.http://www.doiserbia.nb.rs/img/doi/0370-8179/2007/0370-81790708401M.pdfcardiac myxomasurgical treatmentresults |
| spellingShingle | Mikić Aleksandar Obrenović-Kirćanski Biljana Kočica Mladen Vraneš Mile Lačković Vesna Velinović Miloš Marković Miroslav Kovačević Nataša Đukić Petar Cardiac myxoma: The influence of preoperative clinical presentation and surgical technique on late outcome Srpski Arhiv za Celokupno Lekarstvo cardiac myxoma surgical treatment results |
| title | Cardiac myxoma: The influence of preoperative clinical presentation and surgical technique on late outcome |
| title_full | Cardiac myxoma: The influence of preoperative clinical presentation and surgical technique on late outcome |
| title_fullStr | Cardiac myxoma: The influence of preoperative clinical presentation and surgical technique on late outcome |
| title_full_unstemmed | Cardiac myxoma: The influence of preoperative clinical presentation and surgical technique on late outcome |
| title_short | Cardiac myxoma: The influence of preoperative clinical presentation and surgical technique on late outcome |
| title_sort | cardiac myxoma the influence of preoperative clinical presentation and surgical technique on late outcome |
| topic | cardiac myxoma surgical treatment results |
| url | http://www.doiserbia.nb.rs/img/doi/0370-8179/2007/0370-81790708401M.pdf |
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