Influence of hypothyroidism on renal function of lithium-treated patients
Roberto Lozano, Reyes Marín, María-Jesús Santacruz Pharmacy Department, Aragones Health Service, Zaragoza, SpainSeveral studies have shown that lithium maintenance treatment for bipolar disorder (BD) is associated with chronic kidney disease (CKD).1–3 Thre...
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Format: | Article |
Language: | English |
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Dove Medical Press
2015-12-01
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Series: | Neuropsychiatric Disease and Treatment |
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Online Access: | https://www.dovepress.com/influence-of-hypothyroidism-on-renal-functionnbspof-lithium-treated-pa-peer-reviewed-article-NDT |
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author | Lozano R Marín R Santacruz MJ |
author_facet | Lozano R Marín R Santacruz MJ |
author_sort | Lozano R |
collection | DOAJ |
description | Roberto Lozano, Reyes Marín, María-Jesús Santacruz Pharmacy Department, Aragones Health Service, Zaragoza, SpainSeveral studies have shown that lithium maintenance treatment for bipolar disorder (BD) is associated with chronic kidney disease (CKD).1–3 Three recent and large controlled studies concluded that lithium treatment, within recommended serum levels, may increase the risk of induced end-stage renal disease by twofold1,2 or, alternatively, CKD is associated with BD independent of drug treatment.3 Moreover, review of the safety data on lithium shows a 0–5 mL/min reduction in glomerular filtration rate and a clear reduction in urinary concentrating capacity, during an observation period of 1 year.4 |
first_indexed | 2024-12-20T02:49:51Z |
format | Article |
id | doaj.art-92b8535b18d249928ab1e7e4c076a819 |
institution | Directory Open Access Journal |
issn | 1178-2021 |
language | English |
last_indexed | 2024-12-20T02:49:51Z |
publishDate | 2015-12-01 |
publisher | Dove Medical Press |
record_format | Article |
series | Neuropsychiatric Disease and Treatment |
spelling | doaj.art-92b8535b18d249928ab1e7e4c076a8192022-12-21T19:56:04ZengDove Medical PressNeuropsychiatric Disease and Treatment1178-20212015-12-012016Issue 1252725089Influence of hypothyroidism on renal function of lithium-treated patientsLozano RMarín RSantacruz MJRoberto Lozano, Reyes Marín, María-Jesús Santacruz Pharmacy Department, Aragones Health Service, Zaragoza, SpainSeveral studies have shown that lithium maintenance treatment for bipolar disorder (BD) is associated with chronic kidney disease (CKD).1–3 Three recent and large controlled studies concluded that lithium treatment, within recommended serum levels, may increase the risk of induced end-stage renal disease by twofold1,2 or, alternatively, CKD is associated with BD independent of drug treatment.3 Moreover, review of the safety data on lithium shows a 0–5 mL/min reduction in glomerular filtration rate and a clear reduction in urinary concentrating capacity, during an observation period of 1 year.4https://www.dovepress.com/influence-of-hypothyroidism-on-renal-functionnbspof-lithium-treated-pa-peer-reviewed-article-NDTLithiumhypothyroidismkidney |
spellingShingle | Lozano R Marín R Santacruz MJ Influence of hypothyroidism on renal function of lithium-treated patients Neuropsychiatric Disease and Treatment Lithium hypothyroidism kidney |
title | Influence of hypothyroidism on renal function of lithium-treated patients |
title_full | Influence of hypothyroidism on renal function of lithium-treated patients |
title_fullStr | Influence of hypothyroidism on renal function of lithium-treated patients |
title_full_unstemmed | Influence of hypothyroidism on renal function of lithium-treated patients |
title_short | Influence of hypothyroidism on renal function of lithium-treated patients |
title_sort | influence of hypothyroidism on renal function nbsp of lithium treated patients |
topic | Lithium hypothyroidism kidney |
url | https://www.dovepress.com/influence-of-hypothyroidism-on-renal-functionnbspof-lithium-treated-pa-peer-reviewed-article-NDT |
work_keys_str_mv | AT lozanor influenceofhypothyroidismonrenalfunctionnbspoflithiumtreatedpatients AT marinr influenceofhypothyroidismonrenalfunctionnbspoflithiumtreatedpatients AT santacruzmj influenceofhypothyroidismonrenalfunctionnbspoflithiumtreatedpatients |