Influence of hypothyroidism on renal function of lithium-treated patients

Roberto Lozano, Reyes Marín, María-Jesús Santacruz Pharmacy Department, Aragones Health Service, Zaragoza, SpainSeveral studies have shown that lithium maintenance treatment for bipolar disorder (BD) is associated with chronic kidney disease (CKD).1–3 Thre...

Full description

Bibliographic Details
Main Authors: Lozano R, Marín R, Santacruz MJ
Format: Article
Language:English
Published: Dove Medical Press 2015-12-01
Series:Neuropsychiatric Disease and Treatment
Subjects:
Online Access:https://www.dovepress.com/influence-of-hypothyroidism-on-renal-functionnbspof-lithium-treated-pa-peer-reviewed-article-NDT
_version_ 1818925981023338496
author Lozano R
Marín R
Santacruz MJ
author_facet Lozano R
Marín R
Santacruz MJ
author_sort Lozano R
collection DOAJ
description Roberto Lozano, Reyes Marín, María-Jesús Santacruz Pharmacy Department, Aragones Health Service, Zaragoza, SpainSeveral studies have shown that lithium maintenance treatment for bipolar disorder (BD) is associated with chronic kidney disease (CKD).1–3 Three recent and large controlled studies concluded that lithium treatment, within recommended serum levels, may increase the risk of induced end-stage renal disease by twofold1,2 or, alternatively, CKD is associated with BD independent of drug treatment.3 Moreover, review of the safety data on lithium shows a 0–5 mL/min reduction in glomerular filtration rate and a clear reduction in urinary concentrating capacity, during an observation period of 1 year.4
first_indexed 2024-12-20T02:49:51Z
format Article
id doaj.art-92b8535b18d249928ab1e7e4c076a819
institution Directory Open Access Journal
issn 1178-2021
language English
last_indexed 2024-12-20T02:49:51Z
publishDate 2015-12-01
publisher Dove Medical Press
record_format Article
series Neuropsychiatric Disease and Treatment
spelling doaj.art-92b8535b18d249928ab1e7e4c076a8192022-12-21T19:56:04ZengDove Medical PressNeuropsychiatric Disease and Treatment1178-20212015-12-012016Issue 1252725089Influence of hypothyroidism on renal function of lithium-treated patientsLozano RMarín RSantacruz MJRoberto Lozano, Reyes Marín, María-Jesús Santacruz Pharmacy Department, Aragones Health Service, Zaragoza, SpainSeveral studies have shown that lithium maintenance treatment for bipolar disorder (BD) is associated with chronic kidney disease (CKD).1–3 Three recent and large controlled studies concluded that lithium treatment, within recommended serum levels, may increase the risk of induced end-stage renal disease by twofold1,2 or, alternatively, CKD is associated with BD independent of drug treatment.3 Moreover, review of the safety data on lithium shows a 0–5 mL/min reduction in glomerular filtration rate and a clear reduction in urinary concentrating capacity, during an observation period of 1 year.4https://www.dovepress.com/influence-of-hypothyroidism-on-renal-functionnbspof-lithium-treated-pa-peer-reviewed-article-NDTLithiumhypothyroidismkidney
spellingShingle Lozano R
Marín R
Santacruz MJ
Influence of hypothyroidism on renal function of lithium-treated patients
Neuropsychiatric Disease and Treatment
Lithium
hypothyroidism
kidney
title Influence of hypothyroidism on renal function of lithium-treated patients
title_full Influence of hypothyroidism on renal function of lithium-treated patients
title_fullStr Influence of hypothyroidism on renal function of lithium-treated patients
title_full_unstemmed Influence of hypothyroidism on renal function of lithium-treated patients
title_short Influence of hypothyroidism on renal function of lithium-treated patients
title_sort influence of hypothyroidism on renal function nbsp of lithium treated patients
topic Lithium
hypothyroidism
kidney
url https://www.dovepress.com/influence-of-hypothyroidism-on-renal-functionnbspof-lithium-treated-pa-peer-reviewed-article-NDT
work_keys_str_mv AT lozanor influenceofhypothyroidismonrenalfunctionnbspoflithiumtreatedpatients
AT marinr influenceofhypothyroidismonrenalfunctionnbspoflithiumtreatedpatients
AT santacruzmj influenceofhypothyroidismonrenalfunctionnbspoflithiumtreatedpatients