Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia
<p>Abstract</p> <p>Background</p> <p>Activation of the peripheral innate immune system stimulates the secretion of CNS cytokines that modulate the behavioral symptoms of sickness. Excessive production of cytokines by microglia, however, may cause long-lasting behavioral...
Hauptverfasser: | , , , , , , , |
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Format: | Artikel |
Sprache: | English |
Veröffentlicht: |
BMC
2008-05-01
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Schriftenreihe: | Journal of Neuroinflammation |
Online Zugang: | http://www.jneuroinflammation.com/content/5/1/15 |