Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia

<p>Abstract</p> <p>Background</p> <p>Activation of the peripheral innate immune system stimulates the secretion of CNS cytokines that modulate the behavioral symptoms of sickness. Excessive production of cytokines by microglia, however, may cause long-lasting behavioral...

Полное описание

Библиографические подробности
Главные авторы: Bailey Michael T, Himler Justin, Hanke Mark, Wynne Angela, Huang Yan, Henry Christopher J, Sheridan John F, Godbout Jonathan P
Формат: Статья
Язык:English
Опубликовано: BMC 2008-05-01
Серии:Journal of Neuroinflammation
Online-ссылка:http://www.jneuroinflammation.com/content/5/1/15