New Insights into Neuroinflammation Involved in Pathogenic Mechanism of Alzheimer’s Disease and Its Potential for Therapeutic Intervention
Alzheimer’s disease (AD) is the most common form of dementia, affecting more than 50 million people worldwide with an estimated increase to 139 million people by 2050. The exact pathogenic mechanisms of AD remain elusive, resulting in the fact that the current therapeutics solely focus on symptomati...
Main Authors: | Tiantian Li, Li Lu, Eloise Pember, Xinuo Li, Bocheng Zhang, Zheying Zhu |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-06-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/11/12/1925 |
Similar Items
-
Role of cGAS–Sting Signaling in Alzheimer’s Disease
by: Manoj Govindarajulu, et al.
Published: (2023-05-01) -
TREM2: Potential therapeutic targeting of microglia for Alzheimer's disease
by: Yueran Li, et al.
Published: (2023-09-01) -
RU.521 mitigates subarachnoid hemorrhage-induced brain injury via regulating microglial polarization and neuroinflammation mediated by the cGAS/STING/NF-κB pathway
by: Jiang Shao, et al.
Published: (2023-09-01) -
Astragaloside IV attenuates neuroinflammation and ameliorates cognitive impairment in Alzheimer’s disease via inhibiting NF-κB signaling pathway
by: Li He, et al.
Published: (2023-02-01) -
Pretreated MSCs with IronQ Transplantation Attenuate Microglia Neuroinflammation via the cGAS-STING Signaling Pathway
by: Yang G, et al.
Published: (2024-03-01)