Beneficial effect of simvastatin on human umbilical vein endothelial cells gap junctions induced by TNF-α

Although simvastatin has been shown to inhibit vascular permeability, which might be amplified via gap junction intercellular communication (GJIC), the underlying mechanism of action remains unclear. In the present study, we investigated the effects and mechanisms of simvastatin on endothelial cells...

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Bibliographic Details
Main Authors: Xiwen Ling, Siyuan Peng, Yaqin Xu, Fujiang Chu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-01-01
Series:Animal Cells and Systems
Subjects:
Online Access:http://dx.doi.org/10.1080/19768354.2021.2023037

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