A novel plasmid-encoded serotype conversion mechanism through addition of phosphoethanolamine to the O-antigen of Shigella flexneri.

A novel plasmid-encoded serotype conversion mechanism through addition of phosphoethanolamine to the O-antigen of Shigella flexneri.

Shigella flexneri is the major pathogen causing bacillary dysentery in developing countries. S. flexneri is divided into at least 16 serotypes based on the combination of antigenic determinants present in the O-antigen. All the serotypes (except for serotype 6) share a basic O-unit containing one N-...

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Main Authors: Qiangzheng Sun, Yuriy A Knirel, Ruiting Lan, Jianping Wang, Sof'ya N Senchenkova, Dong Jin, Alexander S Shashkov, Shengli Xia, Andrei V Perepelov, Qiang Chen, Yan Wang, Haiyin Wang, Jianguo Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3458804?pdf=render

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