Animal Models of Hepatitis B Virus Infection–Success, Challenges, and Future Directions

Animal Models of Hepatitis B Virus Infection–Success, Challenges, and Future Directions

Chronic hepatitis B virus (HBV) infection affects more than 250 million people worldwide, which greatly increases the risk for terminal liver diseases, such as liver cirrhosis and hepatocellular carcinoma (HCC). Even though current approved antiviral therapies, including pegylated type I interferon...

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Bibliographic Details
Main Authors: Yongzhen Liu, Stephanie Maya, Alexander Ploss
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Viruses
Subjects:
hepatitis B virus
hepatitis B
animal model
species tropism
humanized mice
Online Access:https://www.mdpi.com/1999-4915/13/5/777

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