Premature ovarian insufficiency identified as a kidney deficiency and liver constraint pattern treated by Professor Zhiqiang Guo: A retrospective analysis
Objective: To study the efficacy of Professor Zhiqiang Guo's unique sequential herbal therapy in the treatment of premature ovarian insufficiency (POI) of the kidney deficiency and liver constraint pattern. Methods: Ninety patients with POI who consulted with Professor Guo at Dongzimen Hospital...
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| Format: | Article |
| Language: | English |
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Elsevier
2018-10-01
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| Series: | Journal of Traditional Chinese Medical Sciences |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2095754818301376 |
| _version_ | 1797726409393700864 |
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| author | Hong Yang Yue Deng Jun Li Lixuan Guo Yuying Zhu Xinxie Zhong Zilin Long Liuzhong Ye |
| author_facet | Hong Yang Yue Deng Jun Li Lixuan Guo Yuying Zhu Xinxie Zhong Zilin Long Liuzhong Ye |
| author_sort | Hong Yang |
| collection | DOAJ |
| description | Objective: To study the efficacy of Professor Zhiqiang Guo's unique sequential herbal therapy in the treatment of premature ovarian insufficiency (POI) of the kidney deficiency and liver constraint pattern. Methods: Ninety patients with POI who consulted with Professor Guo at Dongzimen Hospital, Beijing University of Chinese Medicine from January 2012 to December 2015 were enrolled. Treatment consisted of sequential therapy using traditional Chinese medicine formulae with the actions of nourishing the liver and kidney. Course of treatment was 3 consecutive menstrual cycles for each participant except for those who became pregnant during treatment. Baseline data including age, course of disease, past medical history, lifestyle, pregnancy outcome, menstrual status (cycle length, menstrual flow duration and volume), as well as gonadal hormone levels before and after treatment were recorded and analyzed. Results: During treatment, 18 (20.0%) participants became pregnant. Symptoms including scanty menstrual flow, irritability, low libido, insomnia and excessive dreaming at night, nightsweats, hot flashes, and depression were markedly alleviated. Changes in follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels at early follicular stage were observed (P = .009 and P = .002, respectively), and FSH/LH differed significantly pre- and posttreatment (P = .044). Conclusion: Professor Guo's sequential Chinese herbal therapy with the actions of nourishing the liver and kidney to treat POI can enhance ovarian function, promote pregnancy, and improve quality of life. Keywords: Premature ovarian insufficiency, Infertility, Traditional Chinese herbal medicinals, Sequential therapy, Nourish the liver and kidney |
| first_indexed | 2024-03-12T10:44:45Z |
| format | Article |
| id | doaj.art-92c1a4720d924e97845f61c8751fab5f |
| institution | Directory Open Access Journal |
| issn | 2095-7548 |
| language | English |
| last_indexed | 2024-03-12T10:44:45Z |
| publishDate | 2018-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Traditional Chinese Medical Sciences |
| spelling | doaj.art-92c1a4720d924e97845f61c8751fab5f2023-09-02T07:37:30ZengElsevierJournal of Traditional Chinese Medical Sciences2095-75482018-10-0154344349Premature ovarian insufficiency identified as a kidney deficiency and liver constraint pattern treated by Professor Zhiqiang Guo: A retrospective analysisHong Yang0Yue Deng1Jun Li2Lixuan Guo3Yuying Zhu4Xinxie Zhong5Zilin Long6Liuzhong Ye7Beijing University of Chinese Medicine, Beijing 100029, ChinaBeijing University of Chinese Medicine, Beijing 100029, ChinaDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China; Corresponding author.Beijing University of Chinese Medicine, Beijing 100029, ChinaBeijing University of Chinese Medicine, Beijing 100029, ChinaBeijing University of Chinese Medicine, Beijing 100029, ChinaBeijing University of Chinese Medicine, Beijing 100029, ChinaCollege of Naturopathic Medicine, 25 Percy Circus, King's Cross, London, WC1X 9EU, United KingdomObjective: To study the efficacy of Professor Zhiqiang Guo's unique sequential herbal therapy in the treatment of premature ovarian insufficiency (POI) of the kidney deficiency and liver constraint pattern. Methods: Ninety patients with POI who consulted with Professor Guo at Dongzimen Hospital, Beijing University of Chinese Medicine from January 2012 to December 2015 were enrolled. Treatment consisted of sequential therapy using traditional Chinese medicine formulae with the actions of nourishing the liver and kidney. Course of treatment was 3 consecutive menstrual cycles for each participant except for those who became pregnant during treatment. Baseline data including age, course of disease, past medical history, lifestyle, pregnancy outcome, menstrual status (cycle length, menstrual flow duration and volume), as well as gonadal hormone levels before and after treatment were recorded and analyzed. Results: During treatment, 18 (20.0%) participants became pregnant. Symptoms including scanty menstrual flow, irritability, low libido, insomnia and excessive dreaming at night, nightsweats, hot flashes, and depression were markedly alleviated. Changes in follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels at early follicular stage were observed (P = .009 and P = .002, respectively), and FSH/LH differed significantly pre- and posttreatment (P = .044). Conclusion: Professor Guo's sequential Chinese herbal therapy with the actions of nourishing the liver and kidney to treat POI can enhance ovarian function, promote pregnancy, and improve quality of life. Keywords: Premature ovarian insufficiency, Infertility, Traditional Chinese herbal medicinals, Sequential therapy, Nourish the liver and kidneyhttp://www.sciencedirect.com/science/article/pii/S2095754818301376 |
| spellingShingle | Hong Yang Yue Deng Jun Li Lixuan Guo Yuying Zhu Xinxie Zhong Zilin Long Liuzhong Ye Premature ovarian insufficiency identified as a kidney deficiency and liver constraint pattern treated by Professor Zhiqiang Guo: A retrospective analysis Journal of Traditional Chinese Medical Sciences |
| title | Premature ovarian insufficiency identified as a kidney deficiency and liver constraint pattern treated by Professor Zhiqiang Guo: A retrospective analysis |
| title_full | Premature ovarian insufficiency identified as a kidney deficiency and liver constraint pattern treated by Professor Zhiqiang Guo: A retrospective analysis |
| title_fullStr | Premature ovarian insufficiency identified as a kidney deficiency and liver constraint pattern treated by Professor Zhiqiang Guo: A retrospective analysis |
| title_full_unstemmed | Premature ovarian insufficiency identified as a kidney deficiency and liver constraint pattern treated by Professor Zhiqiang Guo: A retrospective analysis |
| title_short | Premature ovarian insufficiency identified as a kidney deficiency and liver constraint pattern treated by Professor Zhiqiang Guo: A retrospective analysis |
| title_sort | premature ovarian insufficiency identified as a kidney deficiency and liver constraint pattern treated by professor zhiqiang guo a retrospective analysis |
| url | http://www.sciencedirect.com/science/article/pii/S2095754818301376 |
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