Effects of Autophagy-related Genes and Signal Pathways on Occurrence and Development of Oral Tumors

Autophagy is a highly conservative cellular self-protective behavior dependent on lysosomes, and can be used as an important factor in promoting or preventing cancer, and its effect is related to the type and development of tumors. A full understanding of autophagy pathway is helpful to improve the...

Full description

Bibliographic Details
Main Authors: XUE Rui, GAO Jiping, YAN Xiaoru, XU Guoqiang, SONG Guohua
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2021-05-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
Online Access:http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2021.20.1377
Description
Summary:Autophagy is a highly conservative cellular self-protective behavior dependent on lysosomes, and can be used as an important factor in promoting or preventing cancer, and its effect is related to the type and development of tumors. A full understanding of autophagy pathway is helpful to improve the diagnosis and treatment of tumors. Studies have shown that autophagy is closely related to the occurrence and development of oral tumors. Autophagy-related genes and signal pathways play a dual regulatory role on oral tumors. This article reviews the latest progress in the regulatory mechanism and therapeutic effect of autophagy on oral tumors.
ISSN:1000-8578