Trends in CV mortality among patients with known mental and behavioral disorders in the US between 1999 and 2020
IntroductionPatients with mental disorders are at increased risk of cardiovascular events. We aimed to assess the cardiovascular mortality trends over the last two decades among patients with mental and behavioral co-morbidities in the US.MethodsWe performed a retrospective, observational study usin...
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| Format: | Article |
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Frontiers Media S.A.
2023-11-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1255323/full |
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| author | Tanya Ebert Tanya Ebert Nashed Hamuda Efrat City-Elifaz Efrat City-Elifaz Ofer Kobo Ofer Kobo Ariel Roguin Ariel Roguin |
| author_facet | Tanya Ebert Tanya Ebert Nashed Hamuda Efrat City-Elifaz Efrat City-Elifaz Ofer Kobo Ofer Kobo Ariel Roguin Ariel Roguin |
| author_sort | Tanya Ebert |
| collection | DOAJ |
| description | IntroductionPatients with mental disorders are at increased risk of cardiovascular events. We aimed to assess the cardiovascular mortality trends over the last two decades among patients with mental and behavioral co-morbidities in the US.MethodsWe performed a retrospective, observational study using the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) Multiple Cause of Death dataset. We determined national trends in age-standardized mortality rates attributed to cardiovascular diseases in patients with and without mental and behavioral disorders, from 1999 to 2020, stratified by mental and behavioral disorders subtype [ICD10 codes F], age, gender, race, and place of residence.ResultsAmong more than 18.7 million cardiovascular deaths in the United States (US), 13.5% [2.53 million] were patients with a concomitant mental and behavioral disorder. During the study period, among patients with mental and behavioral disorders, the age-adjusted mortality rate increased by 113.9% Vs a 44.8% decline in patients with no mental disorder (both p<0.05). In patients with mental and behavioral disorders, the age-adjusted mortality rate increased more significantly among patients whose mental and behavioral disorder was secondary to substance abuse (+532.6%, p<0.05) than among those with organic mental disorders, such as dementia or delirium (+6.2%, P− nonsignificant). Male patients (+163.6%) and residents of more rural areas (+128–162%) experienced a more prominent increase in age-adjusted cardiovascular mortality.DiscussionWhile there was an overall reduction in cardiovascular mortality in the US in the past two decades, we demonstrated an overall increase in cardiovascular mortality among patients with mental disorders. |
| first_indexed | 2024-03-11T14:13:22Z |
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| id | doaj.art-92c22eee0c1748b399a9e08fe13d2769 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-03-11T14:13:22Z |
| publishDate | 2023-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-92c22eee0c1748b399a9e08fe13d27692023-11-01T16:44:30ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402023-11-011410.3389/fpsyt.2023.12553231255323Trends in CV mortality among patients with known mental and behavioral disorders in the US between 1999 and 2020Tanya Ebert0Tanya Ebert1Nashed Hamuda2Efrat City-Elifaz3Efrat City-Elifaz4Ofer Kobo5Ofer Kobo6Ariel Roguin7Ariel Roguin8The Ruth and Bruce Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, IsraelDepartment of Psychiatry, Hillel Yaffe Medical Center, Hadera, IsraelDepartment of Cardiology, Hillel Yaffe Medical Center, Hadera, IsraelThe Ruth and Bruce Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, IsraelDepartment of Psychiatry, Hillel Yaffe Medical Center, Hadera, IsraelThe Ruth and Bruce Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, IsraelDepartment of Cardiology, Hillel Yaffe Medical Center, Hadera, IsraelThe Ruth and Bruce Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, IsraelDepartment of Cardiology, Hillel Yaffe Medical Center, Hadera, IsraelIntroductionPatients with mental disorders are at increased risk of cardiovascular events. We aimed to assess the cardiovascular mortality trends over the last two decades among patients with mental and behavioral co-morbidities in the US.MethodsWe performed a retrospective, observational study using the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) Multiple Cause of Death dataset. We determined national trends in age-standardized mortality rates attributed to cardiovascular diseases in patients with and without mental and behavioral disorders, from 1999 to 2020, stratified by mental and behavioral disorders subtype [ICD10 codes F], age, gender, race, and place of residence.ResultsAmong more than 18.7 million cardiovascular deaths in the United States (US), 13.5% [2.53 million] were patients with a concomitant mental and behavioral disorder. During the study period, among patients with mental and behavioral disorders, the age-adjusted mortality rate increased by 113.9% Vs a 44.8% decline in patients with no mental disorder (both p<0.05). In patients with mental and behavioral disorders, the age-adjusted mortality rate increased more significantly among patients whose mental and behavioral disorder was secondary to substance abuse (+532.6%, p<0.05) than among those with organic mental disorders, such as dementia or delirium (+6.2%, P− nonsignificant). Male patients (+163.6%) and residents of more rural areas (+128–162%) experienced a more prominent increase in age-adjusted cardiovascular mortality.DiscussionWhile there was an overall reduction in cardiovascular mortality in the US in the past two decades, we demonstrated an overall increase in cardiovascular mortality among patients with mental disorders.https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1255323/fullcardiovascular mortalitymental and behavioral disorderssubstance abusemental disorderbehavioral disorders |
| spellingShingle | Tanya Ebert Tanya Ebert Nashed Hamuda Efrat City-Elifaz Efrat City-Elifaz Ofer Kobo Ofer Kobo Ariel Roguin Ariel Roguin Trends in CV mortality among patients with known mental and behavioral disorders in the US between 1999 and 2020 Frontiers in Psychiatry cardiovascular mortality mental and behavioral disorders substance abuse mental disorder behavioral disorders |
| title | Trends in CV mortality among patients with known mental and behavioral disorders in the US between 1999 and 2020 |
| title_full | Trends in CV mortality among patients with known mental and behavioral disorders in the US between 1999 and 2020 |
| title_fullStr | Trends in CV mortality among patients with known mental and behavioral disorders in the US between 1999 and 2020 |
| title_full_unstemmed | Trends in CV mortality among patients with known mental and behavioral disorders in the US between 1999 and 2020 |
| title_short | Trends in CV mortality among patients with known mental and behavioral disorders in the US between 1999 and 2020 |
| title_sort | trends in cv mortality among patients with known mental and behavioral disorders in the us between 1999 and 2020 |
| topic | cardiovascular mortality mental and behavioral disorders substance abuse mental disorder behavioral disorders |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1255323/full |
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