Pyroptotic and Necroptotic Cell Death in the Tumor Microenvironment and Their Potential to Stimulate Anti-Tumor Immune Responses

Pyroptotic and Necroptotic Cell Death in the Tumor Microenvironment and Their Potential to Stimulate Anti-Tumor Immune Responses

Cancer remains the second most common cause of death worldwide affecting around 10 million patients every year. Among the therapeutic options, chemotherapeutic drugs are widely used but often associated with side effects. In addition, toxicity against immune cells may hamper anti-tumor immune respon...

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Bibliographic Details
Main Authors: Allan Scarpitta, Ulrich T. Hacker, Hildegard Büning, Olivier Boyer, Sahil Adriouch
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
immunogenic cell death and anti-tumor immunity
pyroptosis
necroptosis
anti-tumor immune responses
tumor immune microenvironment
inflammation and immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.731598/full

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