Comparison of Central Corneal Thickness using Anterior Segment Optical Coherence Tomography Versus Ultrasound Pachymetry
Introduction: Corneal thickness is an important and sensitive indicator of corneal health. It is useful in monitoring corneal diseases such as corneal oedema and keratoconus, and selecting patients for refractive surgery. Central Corneal Thickness (CCT) is a risk factor for Primary Open-Angle Gl...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2017-08-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/10420/25595_CE(RA1)_F(T)_PF1(SY_VT_GG)_PFA(SY_SS).pdf |
| _version_ | 1811336395692703744 |
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| author | Prasanna Venkatesh Ramesh Kirti Nath Jha Krishnagopal Srikanth |
| author_facet | Prasanna Venkatesh Ramesh Kirti Nath Jha Krishnagopal Srikanth |
| author_sort | Prasanna Venkatesh Ramesh |
| collection | DOAJ |
| description | Introduction: Corneal thickness is an important and sensitive
indicator of corneal health. It is useful in monitoring corneal
diseases such as corneal oedema and keratoconus, and selecting
patients for refractive surgery. Central Corneal Thickness (CCT)
is a risk factor for Primary Open-Angle Glaucoma (POAG).
Aim: To compare CCT using ultrasound pachymetry and Anterior
Segment Optical Coherence Tomography (AS-OCT), and also to
find out the reproducibility of AS–OCT readings for both central
and pericentral corneal areas.
Materials and Methods: This prospective cross-sectional study
was conducted on 120 patients above 40 years of age, and with
clinically normal corneas, who underwent CCT measurements
by both ultrasound and AS-OCT. Both the eyes were analysed.
Two measurements by AS-OCT and 25 measurements by
ultrasound pachymetry were taken. The readings were averaged
and compared by paired t-test. Repeatability of the OCT
pachymetry map sector averages, was assessed by pooled
standard deviation, obtained from the two measurements taken
from each eye.
Results: The CCT in right eye by OCT and ultrasound was
516.28±29.76 µm and 532.42±29.71 µm, respectively. The
CCT in left eye by OCT and ultrasound was 515.82±29.88 µm
and 532.36±29.83 µm, respectively. The difference in CCT
measurement by AS-OCT and ultrasound was statistically
significant (p<0.001); mean ultrasound CCT being 16.14 µm and
16.54 µm greater than the mean AS-OCT, CCT in right eye and
left eye respectively. For AS-OCT, intra-session repeatability
was measured. Repeatability of the OCT mapping was 0.01 µm
to 1.6 µm and 0.01 µm to 1.9 µm in the right eye and left eye
respectively.
Conclusion: The CCT measurement by ultrasound pachymetry
gives higher values compared to AS-OCT measurement. Hence,
they cannot be interchangeably used in clinical practice. The ASOCT provides highly repeatable pachymetry map measurements
both centrally and pericentrally. |
| first_indexed | 2024-04-13T17:38:53Z |
| format | Article |
| id | doaj.art-92d266c2ecb146b4bfc7439f29362d2d |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-13T17:38:53Z |
| publishDate | 2017-08-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-92d266c2ecb146b4bfc7439f29362d2d2022-12-22T02:37:15ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-08-01118NC08NC1110.7860/JCDR/2017/25595.10420Comparison of Central Corneal Thickness using Anterior Segment Optical Coherence Tomography Versus Ultrasound PachymetryPrasanna Venkatesh Ramesh0Kirti Nath Jha1Krishnagopal Srikanth2Senior Resident, Department of Ophthalmology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Puducherry, India.Professor, Department of Ophthalmology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Puducherry, India.Professor and Head, Department of Ophthalmology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Puducherry, India.Introduction: Corneal thickness is an important and sensitive indicator of corneal health. It is useful in monitoring corneal diseases such as corneal oedema and keratoconus, and selecting patients for refractive surgery. Central Corneal Thickness (CCT) is a risk factor for Primary Open-Angle Glaucoma (POAG). Aim: To compare CCT using ultrasound pachymetry and Anterior Segment Optical Coherence Tomography (AS-OCT), and also to find out the reproducibility of AS–OCT readings for both central and pericentral corneal areas. Materials and Methods: This prospective cross-sectional study was conducted on 120 patients above 40 years of age, and with clinically normal corneas, who underwent CCT measurements by both ultrasound and AS-OCT. Both the eyes were analysed. Two measurements by AS-OCT and 25 measurements by ultrasound pachymetry were taken. The readings were averaged and compared by paired t-test. Repeatability of the OCT pachymetry map sector averages, was assessed by pooled standard deviation, obtained from the two measurements taken from each eye. Results: The CCT in right eye by OCT and ultrasound was 516.28±29.76 µm and 532.42±29.71 µm, respectively. The CCT in left eye by OCT and ultrasound was 515.82±29.88 µm and 532.36±29.83 µm, respectively. The difference in CCT measurement by AS-OCT and ultrasound was statistically significant (p<0.001); mean ultrasound CCT being 16.14 µm and 16.54 µm greater than the mean AS-OCT, CCT in right eye and left eye respectively. For AS-OCT, intra-session repeatability was measured. Repeatability of the OCT mapping was 0.01 µm to 1.6 µm and 0.01 µm to 1.9 µm in the right eye and left eye respectively. Conclusion: The CCT measurement by ultrasound pachymetry gives higher values compared to AS-OCT measurement. Hence, they cannot be interchangeably used in clinical practice. The ASOCT provides highly repeatable pachymetry map measurements both centrally and pericentrally.https://jcdr.net/articles/PDF/10420/25595_CE(RA1)_F(T)_PF1(SY_VT_GG)_PFA(SY_SS).pdfprimary open-angle glaucomareproducibility2-mm pachymetry map |
| spellingShingle | Prasanna Venkatesh Ramesh Kirti Nath Jha Krishnagopal Srikanth Comparison of Central Corneal Thickness using Anterior Segment Optical Coherence Tomography Versus Ultrasound Pachymetry Journal of Clinical and Diagnostic Research primary open-angle glaucoma reproducibility 2-mm pachymetry map |
| title | Comparison of Central Corneal Thickness using Anterior Segment Optical Coherence Tomography Versus Ultrasound Pachymetry |
| title_full | Comparison of Central Corneal Thickness using Anterior Segment Optical Coherence Tomography Versus Ultrasound Pachymetry |
| title_fullStr | Comparison of Central Corneal Thickness using Anterior Segment Optical Coherence Tomography Versus Ultrasound Pachymetry |
| title_full_unstemmed | Comparison of Central Corneal Thickness using Anterior Segment Optical Coherence Tomography Versus Ultrasound Pachymetry |
| title_short | Comparison of Central Corneal Thickness using Anterior Segment Optical Coherence Tomography Versus Ultrasound Pachymetry |
| title_sort | comparison of central corneal thickness using anterior segment optical coherence tomography versus ultrasound pachymetry |
| topic | primary open-angle glaucoma reproducibility 2-mm pachymetry map |
| url | https://jcdr.net/articles/PDF/10420/25595_CE(RA1)_F(T)_PF1(SY_VT_GG)_PFA(SY_SS).pdf |
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