Prescription factors influencing baloxavir prescription during the 2018/2019 and 2019/2020 seasons: a administrative database study in Japan

Abstract Background We aimed to evaluate the factors associated with baloxavir prescription in Japanese hospitals using a health insurance claim-based database (MDV analyzer), during the 2018/2019 and 2019/2020 influenza seasons. The MDV analyzer contains anonymized claims data from approximately 42...

Full description

Bibliographic Details
Main Authors: Naomi Fujiwara, Takashi Fujiwara, Yuya Ise
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Pharmaceutical Health Care and Sciences
Subjects:
Online Access:https://doi.org/10.1186/s40780-023-00274-1
_version_ 1828041519696707584
author Naomi Fujiwara
Takashi Fujiwara
Yuya Ise
author_facet Naomi Fujiwara
Takashi Fujiwara
Yuya Ise
author_sort Naomi Fujiwara
collection DOAJ
description Abstract Background We aimed to evaluate the factors associated with baloxavir prescription in Japanese hospitals using a health insurance claim-based database (MDV analyzer), during the 2018/2019 and 2019/2020 influenza seasons. The MDV analyzer contains anonymized claims data from approximately 420 Diagnosis Procedure Combination hospitals, and does not contain data from clinics. Methods Data were collected for influenza patients treated with anti-influenza drugs during the 2018/2019 and 2019/2020 influenza seasons. Multivariate analysis was used to identify factors associated with baloxavir prescription. Results During the study period, 322,063 influenza patients were included for analyses. In multivariate analysis, children, female sex, inpatient, hospital bed capacity, and private hospitals were negatively associated with baloxavir prescription. Compared to elderly patients, the adjusted odds ratio (OR) for baloxavir prescription was 0.612 (95% confidence interval (CI), 0.587–0.637) in children aged 6–11 years, and 0.119 (95% CI, 0.111–0.128) in children aged 0–5 years. Compared to small hospitals (bed capacity, 20–299), the adjusted OR for baloxavir prescription was 0.559 (95% CI, 0.540–0.578) in large hospitals (bed capacity, ≥ 500). Conclusion Children, female sex, inpatient, hospital bed capacity, and private hospitals were negatively associated with baloxavir prescription.
first_indexed 2024-04-10T17:17:25Z
format Article
id doaj.art-92d4aa7a4aec4af0b5f04fb4fd2d65c6
institution Directory Open Access Journal
issn 2055-0294
language English
last_indexed 2024-04-10T17:17:25Z
publishDate 2023-02-01
publisher BMC
record_format Article
series Journal of Pharmaceutical Health Care and Sciences
spelling doaj.art-92d4aa7a4aec4af0b5f04fb4fd2d65c62023-02-05T12:19:24ZengBMCJournal of Pharmaceutical Health Care and Sciences2055-02942023-02-01911510.1186/s40780-023-00274-1Prescription factors influencing baloxavir prescription during the 2018/2019 and 2019/2020 seasons: a administrative database study in JapanNaomi Fujiwara0Takashi Fujiwara1Yuya Ise2Department of Pharmacy, Nippon Medical School HospitalDepartment of Public Health Research, Kurashiki Clinical Research InstituteDepartment of Pharmacy, Nippon Medical School HospitalAbstract Background We aimed to evaluate the factors associated with baloxavir prescription in Japanese hospitals using a health insurance claim-based database (MDV analyzer), during the 2018/2019 and 2019/2020 influenza seasons. The MDV analyzer contains anonymized claims data from approximately 420 Diagnosis Procedure Combination hospitals, and does not contain data from clinics. Methods Data were collected for influenza patients treated with anti-influenza drugs during the 2018/2019 and 2019/2020 influenza seasons. Multivariate analysis was used to identify factors associated with baloxavir prescription. Results During the study period, 322,063 influenza patients were included for analyses. In multivariate analysis, children, female sex, inpatient, hospital bed capacity, and private hospitals were negatively associated with baloxavir prescription. Compared to elderly patients, the adjusted odds ratio (OR) for baloxavir prescription was 0.612 (95% confidence interval (CI), 0.587–0.637) in children aged 6–11 years, and 0.119 (95% CI, 0.111–0.128) in children aged 0–5 years. Compared to small hospitals (bed capacity, 20–299), the adjusted OR for baloxavir prescription was 0.559 (95% CI, 0.540–0.578) in large hospitals (bed capacity, ≥ 500). Conclusion Children, female sex, inpatient, hospital bed capacity, and private hospitals were negatively associated with baloxavir prescription.https://doi.org/10.1186/s40780-023-00274-1BaloxavirInfluenzaAdministrative claims
spellingShingle Naomi Fujiwara
Takashi Fujiwara
Yuya Ise
Prescription factors influencing baloxavir prescription during the 2018/2019 and 2019/2020 seasons: a administrative database study in Japan
Journal of Pharmaceutical Health Care and Sciences
Baloxavir
Influenza
Administrative claims
title Prescription factors influencing baloxavir prescription during the 2018/2019 and 2019/2020 seasons: a administrative database study in Japan
title_full Prescription factors influencing baloxavir prescription during the 2018/2019 and 2019/2020 seasons: a administrative database study in Japan
title_fullStr Prescription factors influencing baloxavir prescription during the 2018/2019 and 2019/2020 seasons: a administrative database study in Japan
title_full_unstemmed Prescription factors influencing baloxavir prescription during the 2018/2019 and 2019/2020 seasons: a administrative database study in Japan
title_short Prescription factors influencing baloxavir prescription during the 2018/2019 and 2019/2020 seasons: a administrative database study in Japan
title_sort prescription factors influencing baloxavir prescription during the 2018 2019 and 2019 2020 seasons a administrative database study in japan
topic Baloxavir
Influenza
Administrative claims
url https://doi.org/10.1186/s40780-023-00274-1
work_keys_str_mv AT naomifujiwara prescriptionfactorsinfluencingbaloxavirprescriptionduringthe20182019and20192020seasonsaadministrativedatabasestudyinjapan
AT takashifujiwara prescriptionfactorsinfluencingbaloxavirprescriptionduringthe20182019and20192020seasonsaadministrativedatabasestudyinjapan
AT yuyaise prescriptionfactorsinfluencingbaloxavirprescriptionduringthe20182019and20192020seasonsaadministrativedatabasestudyinjapan