Dynamic interaction of cBid with detergents, liposomes and mitochondria.
The BH3-only protein Bid plays a key role in the induction of mitochondrial apoptosis, but its mechanism of action is still not completely understood. Here we studied the two main activation events of Bid: Caspase-8 cleavage and interaction with the membrane bilayer. We found a striking reversible b...
| Hlavní autoři: | , , , |
|---|---|
| Médium: | Článek |
| Jazyk: | English |
| Vydáno: |
Public Library of Science (PLoS)
2012-01-01
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| Edice: | PLoS ONE |
| On-line přístup: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22540011/?tool=EBI |