Dynamic interaction of cBid with detergents, liposomes and mitochondria.

The BH3-only protein Bid plays a key role in the induction of mitochondrial apoptosis, but its mechanism of action is still not completely understood. Here we studied the two main activation events of Bid: Caspase-8 cleavage and interaction with the membrane bilayer. We found a striking reversible b...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Stephanie Bleicken, Ana J García-Sáez, Elena Conte, Enrica Bordignon
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2012-01-01
Sraith:PLoS ONE
Rochtain ar líne:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22540011/?tool=EBI