Dynamic interaction of cBid with detergents, liposomes and mitochondria.
The BH3-only protein Bid plays a key role in the induction of mitochondrial apoptosis, but its mechanism of action is still not completely understood. Here we studied the two main activation events of Bid: Caspase-8 cleavage and interaction with the membrane bilayer. We found a striking reversible b...
| Main Authors: | , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
Public Library of Science (PLoS)
2012-01-01
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| 丛编: | PLoS ONE |
| 在线阅读: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22540011/?tool=EBI |