Functional Analysis of the P-Type ATPases Apt2-4 from <i>Cryptococcus neoformans</i> by Heterologous Expression in <i>Saccharomyces cerevisiae</i>

Functional Analysis of the P-Type ATPases Apt2-4 from <i>Cryptococcus neoformans</i> by Heterologous Expression in <i>Saccharomyces cerevisiae</i>

Lipid flippases of the P4-ATPase family actively transport phospholipids across cell membranes, an activity essential for key cellular processes such as vesicle budding and membrane trafficking. Members of this transporter family have also been implicated in the development of drug resistance in fun...

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Bibliographic Details
Main Authors: Sarina Veit, Sabine Laerbusch, Rosa L. López-Marqués, Thomas Günther Pomorski
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Fungi
Subjects:
β-subunit
CDC50 protein
functional complementation
heterologous expression
lipid transport
lipid flippase
Online Access:https://www.mdpi.com/2309-608X/9/2/202

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