Lung–infiltrating T helper 17 cells as the major source of interleukin-17A production during pulmonary Cryptococcus neoformans infection

Lung–infiltrating T helper 17 cells as the major source of interleukin-17A production during pulmonary Cryptococcus neoformans infection

Abstract Background IL-17A has emerged as a key player in the pathologies of inflammation, autoimmune disease, and immunity to microbes since its discovery two decades ago. In this study, we aim to elucidate the activity of IL-17A in the protection against Cryptococcus neoformans, an opportunistic f...

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Bibliographic Details
Main Authors: Elaheh Movahed, Yi Ying Cheok, Grace Min Yi Tan, Chalystha Yie Qin Lee, Heng Choon Cheong, Rukumani Devi Velayuthan, Sun Tee Tay, Pei Pei Chong, Won Fen Wong, Chung Yeng Looi
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Immunology
Subjects:
CD4+ T cells
TH17 cells
Macrophages
IL-17A
Cryptococcus neoformans
Online Access:http://link.springer.com/article/10.1186/s12865-018-0269-5

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