Enalapril and endothelial function in arterial hypertension patients of various age

Vasoactive endothelial function (EF) was assessed in 48 patients with arterial hypertension (AH) (18 participants under 60 years, 30 patients older than 60). Enalapril ("Enam", Dr Reddy's, India) effects on EFwere studied. AH patients were characterized by impaired vasoactive EF, corr...

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Main Authors: L. I. Katelnitskaya, L. A. Khaisheva, S. A. Pleskachev
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2005-12-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/2346
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author L. I. Katelnitskaya
L. A. Khaisheva
S. A. Pleskachev
author_facet L. I. Katelnitskaya
L. A. Khaisheva
S. A. Pleskachev
author_sort L. I. Katelnitskaya
collection DOAJ
description Vasoactive endothelial function (EF) was assessed in 48 patients with arterial hypertension (AH) (18 participants under 60 years, 30 patients older than 60). Enalapril ("Enam", Dr Reddy's, India) effects on EFwere studied. AH patients were characterized by impaired vasoactive EF, correlating with age. In older patients, endothelial reaction to nitroglycerin was also disturbed. Three-month "Enam" therapy was associated with EF normalization. In blood pressure-normalizing doses, "Enam "facilitated improvement of initially impaired endothelial cells' sensitivity to shear stress.
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spelling doaj.art-92e9e399da884024ba15ae4a1e35c7692023-03-29T21:23:12Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202005-12-010671762092Enalapril and endothelial function in arterial hypertension patients of various ageL. I. Katelnitskaya0L. A. Khaisheva1S. A. Pleskachev2ГОУ ВПО Ростовский государственный медицинский университет, ЮМЦ клиническая больница № 1 федерального агентства по здравоохранению и социальному развитию, Ростов-на-ДонуГОУ ВПО Ростовский государственный медицинский университет, ЮМЦ клиническая больница № 1 федерального агентства по здравоохранению и социальному развитию, Ростов-на-ДонуГОУ ВПО Ростовский государственный медицинский университет, ЮМЦ клиническая больница № 1 федерального агентства по здравоохранению и социальному развитию, Ростов-на-ДонуVasoactive endothelial function (EF) was assessed in 48 patients with arterial hypertension (AH) (18 participants under 60 years, 30 patients older than 60). Enalapril ("Enam", Dr Reddy's, India) effects on EFwere studied. AH patients were characterized by impaired vasoactive EF, correlating with age. In older patients, endothelial reaction to nitroglycerin was also disturbed. Three-month "Enam" therapy was associated with EF normalization. In blood pressure-normalizing doses, "Enam "facilitated improvement of initially impaired endothelial cells' sensitivity to shear stress.https://russjcardiol.elpub.ru/jour/article/view/2346endotheliumarterial hypertensionenalapril
spellingShingle L. I. Katelnitskaya
L. A. Khaisheva
S. A. Pleskachev
Enalapril and endothelial function in arterial hypertension patients of various age
Российский кардиологический журнал
endothelium
arterial hypertension
enalapril
title Enalapril and endothelial function in arterial hypertension patients of various age
title_full Enalapril and endothelial function in arterial hypertension patients of various age
title_fullStr Enalapril and endothelial function in arterial hypertension patients of various age
title_full_unstemmed Enalapril and endothelial function in arterial hypertension patients of various age
title_short Enalapril and endothelial function in arterial hypertension patients of various age
title_sort enalapril and endothelial function in arterial hypertension patients of various age
topic endothelium
arterial hypertension
enalapril
url https://russjcardiol.elpub.ru/jour/article/view/2346
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AT sapleskachev enalaprilandendothelialfunctioninarterialhypertensionpatientsofvariousage