VEGF-Trap Modulates Retinal Inflammation in the Murine Oxygen-Induced Retinopathy (OIR) Model

VEGF-Trap Modulates Retinal Inflammation in the Murine Oxygen-Induced Retinopathy (OIR) Model

Anti-Vascular Endothelial Growth Factor (VEGF) agents are the first-line treatment for retinal neovascular diseases, which represent the most prevalent causes of acquired vision loss world-wide. VEGF-Trap (Aflibercept, AFL), a recombinant decoy receptor recognizing ligands of both VEGFR-1 and -2, wa...

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Bibliographic Details
Main Authors: Jesús Eduardo Rojo Arias, Vanessa Elisabeth Englmaier, József Jászai
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomedicines
Subjects:
Aflibercept
VEGF-Trap
microglia
retina
inflammation
oxygen-induced retinopathy
Online Access:https://www.mdpi.com/2227-9059/10/2/201

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