Potential Utility of Oral Mucosal Capillaroscopy as an Indicator of Microvascular Damage in Behçet Disease: A Preliminary Study
Introduction: Behçet disease (BD) is an auto-inflammatory condition characterized by multisystemic vasculitis. Oral mucosal capillaroscopy is an easy-to-use, repeatable, non-invasive method for evaluating mucosal microvasculature, contributing to the differential diagnosis and prognosis of various a...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Mattioli1885
2021-09-01
|
| Series: | Dermatology Practical & Conceptual |
| Subjects: | |
| Online Access: | https://dpcj.org/index.php/dpc/article/view/1679 |
| _version_ | 1818383530748542976 |
|---|---|
| author | Abdullah Demirbaş Ömer Faruk Elmas Gözde Ulutaş Demirbaş Mustafa Atasoy Ümit Türsen Torello Lotti |
| author_facet | Abdullah Demirbaş Ömer Faruk Elmas Gözde Ulutaş Demirbaş Mustafa Atasoy Ümit Türsen Torello Lotti |
| author_sort | Abdullah Demirbaş |
| collection | DOAJ |
| description | Introduction: Behçet disease (BD) is an auto-inflammatory condition characterized by multisystemic vasculitis. Oral mucosal capillaroscopy is an easy-to-use, repeatable, non-invasive method for evaluating mucosal microvasculature, contributing to the differential diagnosis and prognosis of various acute and chronic inflammatory diseases.
Objectives: This study aims to characterize and describe the oral labial mucosal capillary findings in patients with BD using handheld dermatoscopy and to investigate the relationship between the capillary findings and the severity of the disease.
Methods: This cross-sectional study included patients with BD and healthy subjects. Capillaroscopic examination of the oral labial mucosa in each subject was performed by a handheld dermatoscope using polarized light. The clinical severity of BD was evaluated using Krause's Clinical Severity Scoring for BD.
Results: Sixty patients with BD and 60 healthy subjects were enrolled in the study. The frequencies of irregular capillaries, microhemorrhages, glomerular vessels, megacapillaries, and tortuous vessels were statistically significantly higher in the patient group when compared to the healthy individuals. In addition, a correlation was detected between the oral mucosal capillaroscopic findings and disease duration, severity, and vascular complications.
Conclusions: Our study is the first to explore the potential role of oral mucosal capillaroscopic examination in patients with BD. Data obtained from this study indicated that oral mucosal capillaroscopy may be a useful tool to demonstrate microvascular damage in patients with BD. |
| first_indexed | 2024-12-14T03:07:50Z |
| format | Article |
| id | doaj.art-92f23a8f21164632b2b557dd121d98ca |
| institution | Directory Open Access Journal |
| issn | 2160-9381 |
| language | English |
| last_indexed | 2024-12-14T03:07:50Z |
| publishDate | 2021-09-01 |
| publisher | Mattioli1885 |
| record_format | Article |
| series | Dermatology Practical & Conceptual |
| spelling | doaj.art-92f23a8f21164632b2b557dd121d98ca2022-12-21T23:19:20ZengMattioli1885Dermatology Practical & Conceptual2160-93812021-09-0110.5826/dpc.1104a116Potential Utility of Oral Mucosal Capillaroscopy as an Indicator of Microvascular Damage in Behçet Disease: A Preliminary StudyAbdullah Demirbaş0Ömer Faruk Elmas1Gözde Ulutaş Demirbaş2Mustafa Atasoy3Ümit Türsen4Torello Lotti5Department of Dermatology, Kütahya Health Sciences University, Kütahya, Turkey Department of Dermatology, Kırıkkale University, Kırıkkale, Turkey Department of Dermatology, Evliya Çelebi Training and Research Hospital, Kütahya, Turkey Health Science University, Kayseri City Hospital, Department of Dermatology, Kayseri, TurkeyMersin University, Department of Dermatology, Mersin, Turkey Department of Dermatology, Guglielmo Marconi University, Rome, ItalyIntroduction: Behçet disease (BD) is an auto-inflammatory condition characterized by multisystemic vasculitis. Oral mucosal capillaroscopy is an easy-to-use, repeatable, non-invasive method for evaluating mucosal microvasculature, contributing to the differential diagnosis and prognosis of various acute and chronic inflammatory diseases. Objectives: This study aims to characterize and describe the oral labial mucosal capillary findings in patients with BD using handheld dermatoscopy and to investigate the relationship between the capillary findings and the severity of the disease. Methods: This cross-sectional study included patients with BD and healthy subjects. Capillaroscopic examination of the oral labial mucosa in each subject was performed by a handheld dermatoscope using polarized light. The clinical severity of BD was evaluated using Krause's Clinical Severity Scoring for BD. Results: Sixty patients with BD and 60 healthy subjects were enrolled in the study. The frequencies of irregular capillaries, microhemorrhages, glomerular vessels, megacapillaries, and tortuous vessels were statistically significantly higher in the patient group when compared to the healthy individuals. In addition, a correlation was detected between the oral mucosal capillaroscopic findings and disease duration, severity, and vascular complications. Conclusions: Our study is the first to explore the potential role of oral mucosal capillaroscopic examination in patients with BD. Data obtained from this study indicated that oral mucosal capillaroscopy may be a useful tool to demonstrate microvascular damage in patients with BD.https://dpcj.org/index.php/dpc/article/view/1679capillaryhandheld dermoscopymucoscopyoral labial mucosaBehçet diseasemicrovascular damage |
| spellingShingle | Abdullah Demirbaş Ömer Faruk Elmas Gözde Ulutaş Demirbaş Mustafa Atasoy Ümit Türsen Torello Lotti Potential Utility of Oral Mucosal Capillaroscopy as an Indicator of Microvascular Damage in Behçet Disease: A Preliminary Study Dermatology Practical & Conceptual capillary handheld dermoscopy mucoscopy oral labial mucosa Behçet disease microvascular damage |
| title | Potential Utility of Oral Mucosal Capillaroscopy as an Indicator of Microvascular Damage in Behçet Disease: A Preliminary Study |
| title_full | Potential Utility of Oral Mucosal Capillaroscopy as an Indicator of Microvascular Damage in Behçet Disease: A Preliminary Study |
| title_fullStr | Potential Utility of Oral Mucosal Capillaroscopy as an Indicator of Microvascular Damage in Behçet Disease: A Preliminary Study |
| title_full_unstemmed | Potential Utility of Oral Mucosal Capillaroscopy as an Indicator of Microvascular Damage in Behçet Disease: A Preliminary Study |
| title_short | Potential Utility of Oral Mucosal Capillaroscopy as an Indicator of Microvascular Damage in Behçet Disease: A Preliminary Study |
| title_sort | potential utility of oral mucosal capillaroscopy as an indicator of microvascular damage in behcet disease a preliminary study |
| topic | capillary handheld dermoscopy mucoscopy oral labial mucosa Behçet disease microvascular damage |
| url | https://dpcj.org/index.php/dpc/article/view/1679 |
| work_keys_str_mv | AT abdullahdemirbas potentialutilityoforalmucosalcapillaroscopyasanindicatorofmicrovasculardamageinbehcetdiseaseapreliminarystudy AT omerfarukelmas potentialutilityoforalmucosalcapillaroscopyasanindicatorofmicrovasculardamageinbehcetdiseaseapreliminarystudy AT gozdeulutasdemirbas potentialutilityoforalmucosalcapillaroscopyasanindicatorofmicrovasculardamageinbehcetdiseaseapreliminarystudy AT mustafaatasoy potentialutilityoforalmucosalcapillaroscopyasanindicatorofmicrovasculardamageinbehcetdiseaseapreliminarystudy AT umittursen potentialutilityoforalmucosalcapillaroscopyasanindicatorofmicrovasculardamageinbehcetdiseaseapreliminarystudy AT torellolotti potentialutilityoforalmucosalcapillaroscopyasanindicatorofmicrovasculardamageinbehcetdiseaseapreliminarystudy |