Applying Self-Supervised Learning to Medicine: Review of the State of the Art and Medical Implementations

Machine learning has become an increasingly ubiquitous technology, as big data continues to inform and influence everyday life and decision-making. Currently, in medicine and healthcare, as well as in most other industries, the two most prevalent machine learning paradigms are supervised learning an...

Full description

Bibliographic Details
Main Authors: Alexander Chowdhury, Jacob Rosenthal, Jonathan Waring, Renato Umeton
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Informatics
Subjects:
Online Access:https://www.mdpi.com/2227-9709/8/3/59
_version_ 1797518834219876352
author Alexander Chowdhury
Jacob Rosenthal
Jonathan Waring
Renato Umeton
author_facet Alexander Chowdhury
Jacob Rosenthal
Jonathan Waring
Renato Umeton
author_sort Alexander Chowdhury
collection DOAJ
description Machine learning has become an increasingly ubiquitous technology, as big data continues to inform and influence everyday life and decision-making. Currently, in medicine and healthcare, as well as in most other industries, the two most prevalent machine learning paradigms are supervised learning and transfer learning. Both practices rely on large-scale, manually annotated datasets to train increasingly complex models. However, the requirement of data to be manually labeled leaves an excess of unused, unlabeled data available in both public and private data repositories. Self-supervised learning (SSL) is a growing area of machine learning that can take advantage of unlabeled data. Contrary to other machine learning paradigms, SSL algorithms create artificial supervisory signals from unlabeled data and pretrain algorithms on these signals. The aim of this review is two-fold: firstly, we provide a formal definition of SSL, divide SSL algorithms into their four unique subsets, and review the state of the art published in each of those subsets between the years of 2014 and 2020. Second, this work surveys recent SSL algorithms published in healthcare, in order to provide medical experts with a clearer picture of how they can integrate SSL into their research, with the objective of leveraging unlabeled data.
first_indexed 2024-03-10T07:35:01Z
format Article
id doaj.art-92f2df9d103749ddbc425298e68f03e1
institution Directory Open Access Journal
issn 2227-9709
language English
last_indexed 2024-03-10T07:35:01Z
publishDate 2021-09-01
publisher MDPI AG
record_format Article
series Informatics
spelling doaj.art-92f2df9d103749ddbc425298e68f03e12023-11-22T13:34:54ZengMDPI AGInformatics2227-97092021-09-01835910.3390/informatics8030059Applying Self-Supervised Learning to Medicine: Review of the State of the Art and Medical ImplementationsAlexander Chowdhury0Jacob Rosenthal1Jonathan Waring2Renato Umeton3Department of Informatics & Analytics, Dana-Farber Cancer Institute, Boston, MA 02215, USADepartment of Informatics & Analytics, Dana-Farber Cancer Institute, Boston, MA 02215, USADepartment of Informatics & Analytics, Dana-Farber Cancer Institute, Boston, MA 02215, USADepartment of Informatics & Analytics, Dana-Farber Cancer Institute, Boston, MA 02215, USAMachine learning has become an increasingly ubiquitous technology, as big data continues to inform and influence everyday life and decision-making. Currently, in medicine and healthcare, as well as in most other industries, the two most prevalent machine learning paradigms are supervised learning and transfer learning. Both practices rely on large-scale, manually annotated datasets to train increasingly complex models. However, the requirement of data to be manually labeled leaves an excess of unused, unlabeled data available in both public and private data repositories. Self-supervised learning (SSL) is a growing area of machine learning that can take advantage of unlabeled data. Contrary to other machine learning paradigms, SSL algorithms create artificial supervisory signals from unlabeled data and pretrain algorithms on these signals. The aim of this review is two-fold: firstly, we provide a formal definition of SSL, divide SSL algorithms into their four unique subsets, and review the state of the art published in each of those subsets between the years of 2014 and 2020. Second, this work surveys recent SSL algorithms published in healthcare, in order to provide medical experts with a clearer picture of how they can integrate SSL into their research, with the objective of leveraging unlabeled data.https://www.mdpi.com/2227-9709/8/3/59self-supervised learninghealthcarerepresentation learningmedicinecomputer visionpathology
spellingShingle Alexander Chowdhury
Jacob Rosenthal
Jonathan Waring
Renato Umeton
Applying Self-Supervised Learning to Medicine: Review of the State of the Art and Medical Implementations
Informatics
self-supervised learning
healthcare
representation learning
medicine
computer vision
pathology
title Applying Self-Supervised Learning to Medicine: Review of the State of the Art and Medical Implementations
title_full Applying Self-Supervised Learning to Medicine: Review of the State of the Art and Medical Implementations
title_fullStr Applying Self-Supervised Learning to Medicine: Review of the State of the Art and Medical Implementations
title_full_unstemmed Applying Self-Supervised Learning to Medicine: Review of the State of the Art and Medical Implementations
title_short Applying Self-Supervised Learning to Medicine: Review of the State of the Art and Medical Implementations
title_sort applying self supervised learning to medicine review of the state of the art and medical implementations
topic self-supervised learning
healthcare
representation learning
medicine
computer vision
pathology
url https://www.mdpi.com/2227-9709/8/3/59
work_keys_str_mv AT alexanderchowdhury applyingselfsupervisedlearningtomedicinereviewofthestateoftheartandmedicalimplementations
AT jacobrosenthal applyingselfsupervisedlearningtomedicinereviewofthestateoftheartandmedicalimplementations
AT jonathanwaring applyingselfsupervisedlearningtomedicinereviewofthestateoftheartandmedicalimplementations
AT renatoumeton applyingselfsupervisedlearningtomedicinereviewofthestateoftheartandmedicalimplementations