Recombinant TSG-6 protein inhibits the growth of capsule fibroblasts in frozen shoulder via suppressing the TGF-β/Smad2 signal pathway
Abstract Background The tumor necrosis factor-stimulated gene-6 (TSG-6) has been confirmed to inhibit inflammation. It is now generally accepted that local inflammatory stimulation around shoulder capsule causes proliferative fibrosis. This study aims to investigate the mechanism of recombinant TSG-...
Main Authors: | Zhongfan Liu, Yongrong Pei, Hao Zeng, Yibo Yang, Meng Que, Yuhui Xiao, Jing Wang, Xiaojun Weng |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-09-01
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Series: | Journal of Orthopaedic Surgery and Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13018-021-02705-x |
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