Physical stability and release properties of lumefantrine amorphous solid dispersion granules prepared by a simple solvent evaporation approach

Physical stability and release properties of lumefantrine amorphous solid dispersion granules prepared by a simple solvent evaporation approach

Amorphous solid dispersions (ASDs) of lumefantrine, which has low aqueous solubility, have been shown to improve bioavailability relative to crystalline formulations. Herein, the crystallization tendency and release properties of a variety of lumefantrine ASD granules, formed on a blend of microcrys...

Full description

Bibliographic Details
Main Authors: Niraj S. Trasi, Sonal V. Bhujbal, Dmitry Y. Zemlyanov, Qi (Tony) Zhou, Lynne S. Taylor
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Lumefantrine
Amorphous solid dispersions
Salt formation
Physical stability
Release
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156720300141

Similar Items

Similar Items