A computational approach to map nucleosome positions and alternative chromatin states with base pair resolution

Understanding chromatin function requires knowing the precise location of nucleosomes. MNase-seq methods have been widely applied to characterize nucleosome organization in vivo, but generally lack the accuracy to determine the precise nucleosome positions. Here we develop a computational approach l...

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Bibliographic Details
Main Authors: Xu Zhou, Alexander W Blocker, Edoardo M Airoldi, Erin K O'Shea
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/16970

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