A computational approach to map nucleosome positions and alternative chromatin states with base pair resolution
Understanding chromatin function requires knowing the precise location of nucleosomes. MNase-seq methods have been widely applied to characterize nucleosome organization in vivo, but generally lack the accuracy to determine the precise nucleosome positions. Here we develop a computational approach l...
Main Authors: | Xu Zhou, Alexander W Blocker, Edoardo M Airoldi, Erin K O'Shea |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-09-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/16970 |
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