Inflammation, Peripheral Signals and Redox Homeostasis in Athletes Who Practice Different Sports
The importance of training in regulating body mass and performance is well known. Physical training induces metabolic changes in the organism, leading to the activation of adaptive mechanisms aimed at establishing a new dynamic equilibrium. However, exercise can have both positive and negative effec...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/9/11/1065 |
| _version_ | 1797549327481044992 |
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| author | Simone Luti Alessandra Modesti Pietro A. Modesti |
| author_facet | Simone Luti Alessandra Modesti Pietro A. Modesti |
| author_sort | Simone Luti |
| collection | DOAJ |
| description | The importance of training in regulating body mass and performance is well known. Physical training induces metabolic changes in the organism, leading to the activation of adaptive mechanisms aimed at establishing a new dynamic equilibrium. However, exercise can have both positive and negative effects on inflammatory and redox statuses. In recent years, attention has focused on the regulation of energy homeostasis and most studies have reported the involvement of peripheral signals in influencing energy and even inflammatory homeostasis due to overtraining syndrome. Among these, leptin, adiponectin, ghrelin, interleukin-6 (IL6), interleukin-1β (IL1β) and tumour necrosis factor a (TNFa) were reported to influence energy and even inflammatory homeostasis. However, most studies were performed on sedentary individuals undergoing an aerobic training program. Therefore, the purpose of this review was to focus on high-performance exercise studies performed in athletes to correlate peripheral mediators and key inflammation markers with physiological and pathological conditions in different sports such as basketball, soccer, swimming and cycling. |
| first_indexed | 2024-03-10T15:13:07Z |
| format | Article |
| id | doaj.art-92fc72ee494c4f789b582c6c087fb58e |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-10T15:13:07Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-92fc72ee494c4f789b582c6c087fb58e2023-11-20T19:12:06ZengMDPI AGAntioxidants2076-39212020-10-01911106510.3390/antiox9111065Inflammation, Peripheral Signals and Redox Homeostasis in Athletes Who Practice Different SportsSimone Luti0Alessandra Modesti1Pietro A. Modesti2Department of Biomedical, Experimental and Clinical Sciences “Mario Serio”, University of Florence, 50134 Florence, ItalyDepartment of Biomedical, Experimental and Clinical Sciences “Mario Serio”, University of Florence, 50134 Florence, ItalyDepartment of Experimental and Clinical Medicine, University of Florence, 50134 Florence, ItalyThe importance of training in regulating body mass and performance is well known. Physical training induces metabolic changes in the organism, leading to the activation of adaptive mechanisms aimed at establishing a new dynamic equilibrium. However, exercise can have both positive and negative effects on inflammatory and redox statuses. In recent years, attention has focused on the regulation of energy homeostasis and most studies have reported the involvement of peripheral signals in influencing energy and even inflammatory homeostasis due to overtraining syndrome. Among these, leptin, adiponectin, ghrelin, interleukin-6 (IL6), interleukin-1β (IL1β) and tumour necrosis factor a (TNFa) were reported to influence energy and even inflammatory homeostasis. However, most studies were performed on sedentary individuals undergoing an aerobic training program. Therefore, the purpose of this review was to focus on high-performance exercise studies performed in athletes to correlate peripheral mediators and key inflammation markers with physiological and pathological conditions in different sports such as basketball, soccer, swimming and cycling.https://www.mdpi.com/2076-3921/9/11/1065cytokinesredox homeostasissport performance |
| spellingShingle | Simone Luti Alessandra Modesti Pietro A. Modesti Inflammation, Peripheral Signals and Redox Homeostasis in Athletes Who Practice Different Sports Antioxidants cytokines redox homeostasis sport performance |
| title | Inflammation, Peripheral Signals and Redox Homeostasis in Athletes Who Practice Different Sports |
| title_full | Inflammation, Peripheral Signals and Redox Homeostasis in Athletes Who Practice Different Sports |
| title_fullStr | Inflammation, Peripheral Signals and Redox Homeostasis in Athletes Who Practice Different Sports |
| title_full_unstemmed | Inflammation, Peripheral Signals and Redox Homeostasis in Athletes Who Practice Different Sports |
| title_short | Inflammation, Peripheral Signals and Redox Homeostasis in Athletes Who Practice Different Sports |
| title_sort | inflammation peripheral signals and redox homeostasis in athletes who practice different sports |
| topic | cytokines redox homeostasis sport performance |
| url | https://www.mdpi.com/2076-3921/9/11/1065 |
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