Activated Microglia in Cortical White Matter Across Cognitive Aging Trajectories

Activated Microglia in Cortical White Matter Across Cognitive Aging Trajectories

Activation of microglia, the primary mediators of inflammation in the brain, is a major component of gliosis and neuronal loss in a number of age-related neurodegenerative disorders, such as Alzheimer’s disease (AD). The role of activated microglia in white matter, and its relationship with cognitiv...

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Bibliographic Details
Main Authors: Tamar Gefen, Garam Kim, Kabriya Bolbolan, Andrew Geoly, Daniel Ohm, Carly Oboudiyat, Ryan Shahidehpour, Alfred Rademaker, Sandra Weintraub, Eileen H. Bigio, M.-Marsel Mesulam, Emily Rogalski, Changiz Geula
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
microglia
white matter
memory
cognitive aging
neurodegeneration
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00094/full

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