Single intravitreal ranibizumab injection in eyes with acute non-arteritic anterior ischemic optic neuropathy

The aim of this study was to evaluate the effect of single intravitreal ranibizumab injection in eyes with acute non-arteritic anterior ischemic optic neuropathy (NAION). The study includes a retrospective analysis of six eyes of six patients diagnosed with NAION. Mean time between visual loss and t...

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Main Authors: Preetam M Samant, Hemalini P Samant, Kamal A Saraiya
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Journal of Clinical Ophthalmology and Research
Subjects:
Online Access:http://www.jcor.in/article.asp?issn=2320-3897;year=2013;volume=1;issue=1;spage=27;epage=28;aulast=Samant
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author Preetam M Samant
Hemalini P Samant
Kamal A Saraiya
author_facet Preetam M Samant
Hemalini P Samant
Kamal A Saraiya
author_sort Preetam M Samant
collection DOAJ
description The aim of this study was to evaluate the effect of single intravitreal ranibizumab injection in eyes with acute non-arteritic anterior ischemic optic neuropathy (NAION). The study includes a retrospective analysis of six eyes of six patients diagnosed with NAION. Mean time between visual loss and the intravitreal injection was 7.8 days (range 2– 15 days). The mean age of patients was 58.2 years (range 45– 63 years). Mean visual acuity gain was two Snellen′s lines at the six-month follow-up. The mean optic nerve head peri-papillary thickness measured with spectral domain optical coherence tomography after one month decreased by an average of 230 microns. No complication related to the injection was observed during six months′ follow-up. Our case series, the fi rst of its type from the Indian subcontinent, shows that patients with acute NAION may benefi t from intravitreal ranibizumab injection.
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spelling doaj.art-930b720ab9f3445cbea59d59113888352022-12-22T00:55:10ZengWolters Kluwer Medknow PublicationsJournal of Clinical Ophthalmology and Research2320-38972013-01-01112728Single intravitreal ranibizumab injection in eyes with acute non-arteritic anterior ischemic optic neuropathyPreetam M SamantHemalini P SamantKamal A SaraiyaThe aim of this study was to evaluate the effect of single intravitreal ranibizumab injection in eyes with acute non-arteritic anterior ischemic optic neuropathy (NAION). The study includes a retrospective analysis of six eyes of six patients diagnosed with NAION. Mean time between visual loss and the intravitreal injection was 7.8 days (range 2– 15 days). The mean age of patients was 58.2 years (range 45– 63 years). Mean visual acuity gain was two Snellen′s lines at the six-month follow-up. The mean optic nerve head peri-papillary thickness measured with spectral domain optical coherence tomography after one month decreased by an average of 230 microns. No complication related to the injection was observed during six months′ follow-up. Our case series, the fi rst of its type from the Indian subcontinent, shows that patients with acute NAION may benefi t from intravitreal ranibizumab injection.http://www.jcor.in/article.asp?issn=2320-3897;year=2013;volume=1;issue=1;spage=27;epage=28;aulast=SamantIntravitreal ranibizumabnon-arteritic anterior ischemic optic neuropathyoptic nerve head peri-papillary thickness
spellingShingle Preetam M Samant
Hemalini P Samant
Kamal A Saraiya
Single intravitreal ranibizumab injection in eyes with acute non-arteritic anterior ischemic optic neuropathy
Journal of Clinical Ophthalmology and Research
Intravitreal ranibizumab
non-arteritic anterior ischemic optic neuropathy
optic nerve head peri-papillary thickness
title Single intravitreal ranibizumab injection in eyes with acute non-arteritic anterior ischemic optic neuropathy
title_full Single intravitreal ranibizumab injection in eyes with acute non-arteritic anterior ischemic optic neuropathy
title_fullStr Single intravitreal ranibizumab injection in eyes with acute non-arteritic anterior ischemic optic neuropathy
title_full_unstemmed Single intravitreal ranibizumab injection in eyes with acute non-arteritic anterior ischemic optic neuropathy
title_short Single intravitreal ranibizumab injection in eyes with acute non-arteritic anterior ischemic optic neuropathy
title_sort single intravitreal ranibizumab injection in eyes with acute non arteritic anterior ischemic optic neuropathy
topic Intravitreal ranibizumab
non-arteritic anterior ischemic optic neuropathy
optic nerve head peri-papillary thickness
url http://www.jcor.in/article.asp?issn=2320-3897;year=2013;volume=1;issue=1;spage=27;epage=28;aulast=Samant
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AT kamalasaraiya singleintravitrealranibizumabinjectionineyeswithacutenonarteriticanteriorischemicopticneuropathy